Fosaprepitant dimeglumine CAS NO 265121-04-8
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Keywords
265121-04-8 Fosaprepitant dimeglumine Fosaprepitant dimeglumine CAS NO 265121-04-8
Quick Details
- Appearance:White powder
- Application:Pharmaceutical intermediates
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- ProductionCapacity:20000|Kilogram|Day
- Storage:Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
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Fosaprepitant dimeglumine CAS NO 265121-04-8
Details:
| Fosaprepitant dimeglumine Basic information |
| Product Name: | Fosaprepitant dimeglumine |
| Synonyms: | Fosaprepitant-d4 Dimeglumine;D-Glucitol, 1-deoxy-1-(methylamino)-, (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4- morpholinyl)methyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)phosphonate (2:1) (salt);Mk-0517;Fosaprepitant dimeglumine(MK-0517);Fosaprepitant dimeglumine(MK0517,Emend, Inemend);Phosphonic acid, (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:2);Unii-D35fm8T64x;[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(MethylaMino)-D-glucitol |
| CAS: | 265121-04-8 |
| MF: | C60H78F14N10O20P2 |
| MW: | 1587.2414868 |
| EINECS: | 682-419-4 |
| Product Categories: | Other APIs;Inhibitors |
| Mol File: | 265121-04-8.mol |
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| Fosaprepitant dimeglumine Chemical Properties |
| Safety Information |
| Fosaprepitant dimeglumine Usage And Synthesis |
| Uses | Fosaprepitant is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist |
| Definition | ChEBI: An organoammonium salt obtained by reaction of fosaprepitant with two equivalents of 1-deoxy-1-(methylamino)-D-glucitol. A substance P/neurokinin 1 (NK1) receptor antagonist. Aprepitant is a selective high-affinity antagonist of human subs ance P/neurokinin 1 (NK1) receptors. Aprepitant has little or no affinity for serotonin (5-HT3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting and postoperative nausea and vomiting |
Fosaprepitant dimeglumine CAS NO 265121-04-8
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