Artemisinin, Artemisinine 99%, CAS No.: 63968-64-9

Details:

Pharmaceutical Raw Materials Artemisinin powder CAS 63968-64-9

Artemisinin:
Artemisinin--CAS NO. 63968-64-9
Artemisinin--Molecular Formula C15H22O5
Artemisinin--Molecular Weight 282.33
Artemisinin--Purity 99%
Artemisinin--Grade Pharmaceutical Grade
Artemisinin--Appearance White Crystalline Powder

WHAT IS Artemisinin

The treatment of malaria drug artemisinin is a best drug for treating malaria, is a sesquiterpene lactone drug derived from Artemisia annua L in the peroxide group, has high effect and heat, deficiency heat, back protozoacidal, low toxicity characteristics, at present around the world using artemisinin based combination therapy for treatment of malaria the effect of (ACT) reached more than 90%, has been widely used in the treatment of malaria in the world. It has a rapid and rapid killing effect on the erythrocytic stage of Plasmodium vivax and can rapidly control clinical seizures and symptoms. At the same time, chicken coccidiosis, porcine red cell disease, toxoplasmosis, fever of yin deficiency and damp heat jaundice have prominent curative effects on vivax malaria, falciparum malaria, cerebral malaria and chloroquine resistant malaria.


Artemisinin is Chinese first successfully developed by scientists, is the effective monomer separated from the treatment of malaria in China folk herbs of Artemisia annua, one of the major countries of the China raw materials of plant growth, development demand originated in 60s in Vietnam, has been on the chlorine Kui Plasmodium specific drug resistance, then not many soldiers died in the war, but died of malaria.


Because of the presence of artemisinin resistance in the border areas of Cambodia and Thailand, the WHO advocated the use of compound preparations rather than monomer preparations. In this environment, the world's first drug artemisinin based antimalarial compound drug compound artemether in Chinese successfully developed, but because of Chinese pharmaceutical companies for intellectual property rights attention degree is not enough, leading to the current world only Novartis has WHO approved riamet foreign sales right will provide WHO with the drug cost price, has won wide acclaim from the international community, in this business station in our country can only play a big role of raw medicine production.


COA

Application
Artemisia used as antimalarial drugs, clinical application proves that artemisinin and its derivatives on the effects between malaria and falciparum malaria, especially arteannuin (Artemtherin), which reduced cell clones of Plasmodium is stronger than other artemisinin drugs to kill. The utility model has the advantages of high efficiency, quick acting, low toxicity and no cross resistance with chloroquine, and can be used not only for treatment, but also for emergency treatment. 



Applicable to all kinds of malaria, such as falciparum malaria, vivax malaria, chloroquine resistant malaria and cerebral malaria. Dangerous type. Most notably, dihydroartemisinin and its tablets. The efficacy of this medicine was 10 times higher than that of artemisinin, and the recurrence rate was only 1.95%. Therefore, it was named China's ten largest scientific and technological achievement in 1992. Artemisinin and its derivatives are not only an excellent antimalarial drug, but also potentially attractive in the treatment of other diseases. 



The animal experiments showed that artemisinin in the treatment of Clonorchis sinensis, killing rate reached 100%; the treatment of animal schistosomiasis, pest control rate of 33.8-99.3%. The total effective rate of artemisinin in the treatment of disk lupus erythematosus is 90%. The curative effect of the treatment of dengue fever is obviously superior to that of morpholine, guanidine and other Western medicines. The study also showed that artemisinin can significantly improve lymphocyte conversion and enhance the immune function of antibodies. No product was found to have toxic effects on heart, liver and kidney. There were no obvious side effects in the clinic.