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Keywords
137281-23-3 Pemetrexed Hydrate Pemetrexed Hydrate CAS NO137281-23-3
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Pemetrexed Hydrate CAS NO137281-23-3
Details:
| N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt Basic information |
| Product Name: | N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt |
| Synonyms: | (S)-2-(4-(2-(2-AMino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl)benzaMido)pentanedioic acid;N-[4-[2-(2-aMino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoyl]L-GlutaMic acid (PeMetrexed acid);N-[4-[2-(2-AMino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoyl]-L-glutaMic acid;(S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo-[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedi;N-[4-[2-(2-Amino-4,7;(2R)-2-{[4-(2-{2-aMino-4-oxo-1H,4H,7H-pyrrolo[2,3-d]pyriMidin-5-yl}ethyl)phenyl]forMaMido}pentanedioic acid;N-(4- 2-(2-AMino-4,7-Dihydro-4-oxo-1H-pyrrol...;PeMetrexed disodiuM INT-6 |
| CAS: | 137281-23-3 |
| MF: | C20H21N5O6 |
| MW: | 427.41 |
| EINECS: | 680-625-9 |
| Product Categories: | API;CIALIS;Anti-cancer & immunity |
| Mol File: | 137281-23-3.mol |
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| N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt Chemical Properties |
| Merck | 14,7077 |
| CAS DataBase Reference | 137281-23-3(CAS DataBase Reference) |
| Safety Information |
| RTECS | LZ9950100 |
| Hazardous Substances Data | 137281-23-3(Hazardous Substances Data) |
| N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt Usage And Synthesis |
| Chemical Properties | Off-White Solid |
| Uses | N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid, referred to as Pemetrexed, is used in the treatment of malignant pleural mesothelioma (MPM). |
| Uses | erectile dysfunction therapy |
| Definition | ChEBI: An N-acylglutamic acid in which the N-acyl group is specified as 4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl. Inhibits thymidylate synthase (TS), 421 di ydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). |
Pemetrexed Hydrate CAS NO137281-23-3
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