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Furacilin 59-87-0 59-87-0 Furacilin

Quick Details

Appearance:White Crystalline Powder
Application: It Can Be Used As Pharmaceutical Intermediates Etc
PackAge:100g/ bag, 2 kg/ bag, 25kg/ carton or as required
ProductionCapacity:1000|Metric Ton|Month
Storage:Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
Transportation:By DHL, TNT, FedEx, HKEMS, UPS, Etc

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High Purity Veterinary Drugs CAS 59-87-0 Furacilin with best price

Basic information:

CAS No.59-87-0
Chemical Name:Furacilin
Synonyms: NF;NFZ;NFS;NF-7;Nefco;acutol;Amifur;Chixin;Mammex;U-6421
CBNumber: CB0492724
Molecular Formula:C6H6N4O4
Formula Weight:198.14
Melting point:242-244 °C(lit.)
Flash point: 2 °C
storage temp: 2-8°C
Water Solubility: <0.1 g/100 mL at 19 ºC
Sensitive: Light Sensitive
Merck: 14,6600

COA:

Product name	Furacilin
CAS No.	59-87-0	Outer Packing	25KG
Production date	17.5	Shelf life	20.5
Standard adopted	BP2015
Items of analysis	Specification	Results
Appearance	A yellow or brownish-yellow,Crystalline powder	Conforms
A	Carry out the test protected from bright light. Use
Appearance	A yellow or brownish-yellow,Crystalline powder,	Conforms
A	Carry out the test protected from bright light.use the solution prepared for the assay.examined between 220 nm and 400 nm(2.2.25),the solution shows two absorption maxima ,at 260 nm and 375nm.The ratio of the absorbance measured at the maximum at 375 nm to that measured at the maximum at 260 nm is 1.15 to 1.13	Conforms
B	Examine by infrared absorption spectrophotometry (2.2.24), comparing with the spectrum obtained with nitrofural CRS. Examine the substances prepared as discs.	Conforms
C	Examine by thin-layer chromatography (2.2.27),using silica gel G R as the coating substance.	Conforms
D	Dissolve about 1 mg in 1 ml of dimethylformamide R and add 0.1 ml of alcoholic potassium hydroxide solution R. A violet-red colour is produced.	Conforms
PH:	5.0~7.0	6.22
5-nitro-2-furfuraldizine	Not more than 0.5%	Conforms
Individual impurity	Not more than 0.5%	Conforms
Total impurities	Not more than 1.0%	Conforms
Loss on drying	Not more than 0.25%	0.35%
Sulphated ash	Not more than 0.1%.	0.07%
Assay	97.0~103.0%	99.16%
Conclusion	Qualified

Medical Uses:

Human Use

Nitrofurazone was previously available as a prescription in the U.S., and was indicated as a topical solution, topical cream, or topical ointment for the treatment of bacterial skin infections, wounds, burns, and ulcers.It was also used as a prophylactic measure to prevent infection that could potentially result in skin graft rejection.

Animal Use

Nitrofurazone is indicated for topical use in dogs, cats, and horses, for the treatment or prophylactic treatment of superficial bacterial infections, burns, and cutaneous ulcers.Preparations for treating infections, such as fin rot, in ornamental fish are also still commercially available.The use of nitrofurazone, or related compounds, in animals raised for human consumption has been strictly banned.

Mechanism Of Action:

The exact mechanism of action is unknown. Furacilin inhibits several bacterial enzymes, especially those involved in the aerobic and anaerobic degradation of glucose and pyruvate. This activity is believed also to affect pyruvate dehydrogenase, citrate synthetase, malate dehydrogenase, glutathione reductase, and pyruvate decarboxylase.

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High Purity Veterinary Drugs CAS 59-87-0 Furacilin with Best Price