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59-05-2 Methotrexate C20H22N8O5
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Anti-Cancer Drug Orange Powder Methotrexate (MTX) / Amethopterin for Treating Cancer
Product Name: Methotrexate
Product Details:
Product Name |
Methotrexate |
Alias |
Methotrexate;Methoxtrexate;Trexall |
CAS |
59-05-2 |
MF |
C20H22N8O5 |
MW |
454.44 |
EINECS |
200-413-8 |
Purity |
99% |
Appearance |
Orange Powder |
Certification |
ISO 9001, USP, BP |
Standard |
USP Standard |
Usage |
Used as a antineoplastic and antirheumatic. A folic Acid antagonist |
Packing |
Discreet packing ways as your requirement, 100% go through |
Storage |
Store in cool and dry area and keep away from direct sunlight |
Description:
Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant.It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions. Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, and osteosarcoma. Types of autoimmune diseases it is used for include psoriasis, rheumatoid arthritis, and Crohn's disease. It can be given by mouth or by injection.
Methotrexate interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells. Methotrexate is used to treat certain types of cancer of the breast, skin, head and neck, or lung. It is also used to treat severe psoriasis and rheumatoid arthritis. Methotrexate is usually given after other medications have been tried without successful treatment of symptoms. Methotrexate may also be used for purposes not listed in this medication guide.
Application:
Methotrexate is used as a disease-modifying treatment for some autoimmune diseases, including rheumatoid arthritis, juvenile dermatomyositis, psoriasis, psoriatic arthritis, lupus, sarcoidosis, Crohn's disease (although a recent review has raised the point that it is fairly underused in Crohn's disease), eczema and many forms of vasculitis. Although originally designed as a chemotherapy drug (using high doses), in low doses, methotrexate is a generally safe and well tolerated drug in the treatment of certain autoimmune diseases. Because of its effectiveness, low-dose methotrexate is now first-line therapy for the treatment of rheumatoid arthritis. Weekly doses are beneficial for 12 to 52 weeks duration therapy, although discontinuation rates are as high as 16% due to adverse effects. Although methotrexate for autoimmune diseases is taken in lower doses than it is for cancer, side effects such as hair loss, nausea, headaches, and skin pigmentation are still common. Use of low doses of methotrexate together with NSAIDS such as aspirin or paracetamol is relatively safe in people being treated for rheumatoid arthritis, if adequate monitoring is done.
Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis that has not responded to other treatments. It may also be used to control juvenile rheumatoid arthritis. Methotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the growth of cancer cells and suppressing the immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function.
Benefit:
Generalized anxiety disorder
Major depressive disorder
Nerve pain caused by diabetes
Fibromyalgia pain
Chronic muscle and joint pain
COA:
Product name |
METHOTREXATE |
||
CAS No. |
59-05-2 |
Outer Packing |
1kg/foil bag |
Standard adopted |
USP 30 |
||
Items of analysis |
Specification |
Results |
|
Description |
Orange or yellow crystalline powder |
Conforms |
|
Identification |
IR , UV |
Conforms |
|
Water |
Not more than 12.0% |
9.7% |
|
Residue on ignition |
Not more than 0.1% |
0.06% |
|
Chromatographic purity |
Total: Not more than 2.0% |
0.81 % |
|
Chromatographic purity |
Individual: Not more than 0.5% |
0.24% |
|
Specific rotation |
Between +19°and +24° |
+22.5° |
|
Organic volatile impurities |
Ethanol: not more than 0.5% |
0.35% |
|
Organic volatile impurities |
Aether : not more than 0.5% |
0.19% |
|
Assay |
Between 98.0% and 102.0% |
99.55% |
|
Solubility |
practically insoluble in water,chloroform,ethanol and ether, freely soluble in watery alkali, soluble in watery hydrochloric acid. |
Conforms |
|
Conclusion |
Qualified |
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
2 . Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.
3 . Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate
4 . Warm after-sale service Any of your question would be solved for the first as soon as possible.
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