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Propofol 2078-54-8 2078-54-8 Propofol
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Details:
Propofol is used for induction and maintenance (in some cases) of anesthesia, having largely replaced sodium thiopental. It can also be administered as part of an anaesthesia maintenance technique called total intravenous anesthesia using either manually-programmed infusion pumps or computer-controlled infusion pumps in a process called target controlled infusion or TCI. Propofol is also used to sedate individuals who are receiving mechanical ventilation but are not undergoing surgery, such as patients in theintensive care unit. In critically ill patients, propofol has been found to be superior to lorazepam both in effectiveness and overall cost.
Application:
DIPRIVAN Injectable Emulsion is definitely an intravenous sedative-hypnotic agent to be used in the induction and repair off anesthesia or sedation. Intravenous injection of your therapeutic dose of propofol induces hypnosis, with minimal excitation, usually within 40 seconds from the beginning of injection (some time for one arm-brain circulation). Much like other rapidly acting intravenous anestheticagents, the half-time from the blood-brain equilibration is approximately 1-3 minutes, accounting for the rate of induction of anesthesia. The mechanism of action, like several general anesthetics, is poorly understood. However, propofol is believed to produce its sedative/anesthetic effects through the positive modulation from the
Usages:
Two molecules of deferasirox are capable of binding to 1 atom of iron which are subsequently eliminated by fecal excretion. Its low molecular weight and high lipophilicity allows the drug to be taken orally unlike deferoxamine which has to be administered by IV route (intravenous infusion). Together with deferiprone, deferasirox seems to be capable of removing iron from cells (cardiac myocytes and hepatocytes) as well as removing iron from the blood.
Deferasirox COA:
Item | Specification |
Specific rotation | +39.5 to +41.5° |
State of solution(transmittance) | Clear 98.0% min. |
Chloride[cl] | 0.020% max. |
Ammonium [NH4] | 0.02% max. |
Sulfate[SO4] | 0.020% max |
Iron[Fe] | 10ppm max. |
Heavy metals [Pb] | 10ppm max |
Arsenic[As2O3] | 1ppm max |
Other amino acids | Chromatographically not detectable |
Loss on drying | 0.20% max. |
Residue on ignition[sulfated] | 0.10% max. |
Assay | 99.0% min |
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High Quality Pharmaceutical Anesthetic Propofol CAS 2078-54-8
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