Pharm Raw Materials Sulbactam Sodium / CAS: 69388-84-7 

                 

 

Description:

Sulbactam sodium salt is a β-lactamase inhibitor that has similar characteristics as ampicillin.
 
Product name: Sulbactam sodium

CAS NO.: 69388-84-7

EINECS NO.:  273-984-4

MF:  C₈H₁₀NNaO₅S

MW: 255.23

Appearance:White or off white powder or crystal. 

Melting point:  >230 °C

Assay:99%min

 

Uses

A semi-synthetic β-lactamase inhibitor. It is used in combination with β-lactam antibiotics as antibacterial.

 

Application:


Sulbactam can be used in combination with ampicillin and cefoperazone to suppress B-lactamase activity when used in Agrobacterium mediated plant genetic modifications.




Specification:

 

ITEMS	STANDARD	RESULTS
Characters	White or almost white crystalline  granule and powder	A white crystalline granule and powder
Identification	(1)  The  spectrum obtained with the substance to be examined corresponds with that obtained with reference standard (2)  Should meet the requirement under water	Comforms
Appearance of solution	≤reference suspension II (1 mol/L hydrochloric acid) ≤reference suspension II (2 mol/L ammonia)	≤Reference suspension I   ≤Reference suspension I
PH	3.5~5.5	4.4
Specific optical rotation	+280~ +305	+296
Related substances	Any impurity≤1.0%	0.26%
Dimethylaniline	≤20ppm	Complies (not used in process)
Water	12.0%~15.0%	13.3%
Sulphated ash	≤0.5%	0.07%
Bulk density	0.45g/ml - 0.65g/ml	0.57g/ml
Tapped density	≥0.65g/ml	0.76g/ml
Assay	96.0%~102.0%  C16H19N3O4S (calculated on the anhydrous basis)	99.7%

COA:

ITEMS	STANDARD	RESULTS
Characters	White or almost white crystalline granule and powder	A white crystalline granule and powder
Identification	(1) The spectrum obtained with the substance to be examined corresponds with that obtained with reference standard (2) Should meet the requirement under water	Comforms
Appearance of solution	≤reference suspension II (1 mol/L hydrochloric acid) ≤reference suspension II (2 mol/L ammonia)	≤Reference suspension I ≤Reference suspension I
PH	3.5~5.5	4.4
Specific optical rotation	+280~ +305	+296
Related substances	Any impurity≤1.0%	0.26%
Dimethylaniline	≤20ppm	Complies (not used in process)
Water	12.0%~15.0%	13.3%
Sulphated ash	≤0.5%	0.07%
Bulk density	0.45g/ml - 0.65g/ml	0.57g/ml
Tapped density	≥0.65g/ml	0.76g/ml
Assay	96.0%~102.0% C16H19N3O4S (calculated on the anhydrous basis)	99.7%

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