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Spiramycin Spiramycin powder 99% Spiramycin
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Spiramycin with EP standard CAS No 8025-81-8
English name: spiramycin from streptomyces sp.
Molecular Formula:C43H74N2O14
Molecular Weight:843.0527
CAS Registry Number:8025-81-8
EINECS:232-429-6
Quality:BP/EP/USP
Density:1.21g/cm3
Boiling point:913.7°C at 760 mmHg
Refractive index:1.549
Flash point:506.4°C
Vapour Pressur:0mmHg at 25°C
Appearance:White or light yellow powder.
Application:Belong to antibiotic medicines for staphylococcus, s. pyogenes, streptococcus pneumoniae, syphilis helicoid etc infection.
What is spiramycin
Spiramycin, white or slightly yellow powder, slightly odor; Micro-hygroscopic;
This product is dissolved in methanol, ethanol, acetone or ether, almost insoluble in water, insoluble in petroleum ether.
It is a macrolide antibiotic obtained from the broth of Streptomyces ambofaciens.
Spiramycin is acetate acetate of acetylspiramycin, which shows strong antibacterial effect after oral administration of deacetylation. Spiramycin is a very strong bacteriostatic agent that only acts as a bactericidal agent at very high concentrations.
Spiramycin is a macrolide antibiotic. It is used to treat toxoplasmosis and various other infections of soft tissues. Although used in Europe, Canada and Mexico, spiramycin is still considered an experimental drug in the United States, but can sometimes be obtained by special permission from the FDA for toxoplasmosis in the first trimester of pregnancy.
What function & Application does spiramycin have
Spiramycin has a strong antibacterial effect in vivo and post-antibacterial effect (PAE), can enhance the phagocytosis of phagocytic cells, and is widely distributed in the body. This product is higher than the concentration of erythromycin in tissue cells, and the side effects are less than erythromycin. This product can be used to treat ear, nose, throat and respiratory tract infections caused by gram-positive bacteria and certain gram-negative bacteria. It is suitable for the treatment of otitis media, periodontitis, acute sinusitis and other oral and otolaryngitis caused by sensitive bacteria. Section infection. It can also be used to treat toxoplasmosis.
Specification
Items | Specifications | Results |
Appearance | A white or slightly yellowish powder | White powder |
Identification | Conform | |
A. UV Spectrum | The specific absorbance at the maximum (232nm) is about 340. | |
B. TLC | Corresponds to reference solution. | |
C. Color Reaction | Brown colour. | |
pH | 8.5-10.5 | 9.6 |
Specific optical rotation | -80°- -85°(dried substance) | -83° |
Composition (HPLC) | SpiramycinⅠ≥80.0 % | 88.20% |
SpiramycinⅡ≤5.0 % | 0.30% | |
SpiramycinⅢ≤10.0 % | 3.70% | |
Total Spiramycins ≥90.0 % | 92.20% | |
Related substances (HPLC) | ≤2.0 % | Conform |
Heavy metals | ≤20ppm | Conform |
Loss on drying | ≤3.5 % | 1.40% |
Sulphated ash | ≤0.1 % | Conform |
Assay (wet substance) | No limits (IU/mg) | 4305 IU/mg |
Assay (dried substance) | ≥4100 IU/mg | 4366 IU/mg |
CONCLUSION | CONFORM TO EP VII |
Before-Sale Service:
---Any inquiries will be replied within 12 hours.
---Golden Manufactory underISO/GMPwithlarge stock.
---Dedication to quality,Wehavestrictqualitycontrolsystem.
---OEM/ODM Available.
---Sample is available for your evaluation & Formulation development.
---LowMOQ: NoworryaboutthebigMOQ.
---FastDelivery: Narmolly grt it within 7-10 days after confirming the order.
---Convenient Payment: Trade Assurance on Alibaba(Visa or Credit card), or TT
After-Sale Service:
---International Authorized Third-Party Test For The Products You Demand.
---60 Days Warranty of quality of goods.
What's more:
Looking forward to having a long-term cooperation with us in China !
Welcome to visit our factory ! ! !
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