Sirolimus high purity Sirolimus high quality Sirolimus
tems |
standard |
result |
appearance |
white or off-white crystalline powder |
complies |
loss on drying |
0.5% max |
0.19% |
heavy metals |
20ppmmax |
complies |
individual impurity |
1.5% max |
0.27% |
residue on ignition |
0.2% max |
0.07% |
total impurities |
2.0% max |
0.54% |
isomer |
5.0% max |
2.34% |
residual solvent |
6.0 max |
0.9 |
ethanol |
200ppmmax |
complies |
ethyl acetate |
200ppmmax |
complies |
cyclohexane |
200ppmmax |
complies |
acetone |
200ppmmax |
complies |
ether |
200ppmmax |
complies |
purity |
calculated trans- and cis-stereoisomer of sirolimus on the dired basis, nlt 98.5% |
99.48% |
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