Min.Order / FOB Price:Get Latest Price
25 Kilogram |
FOB Price:USD 820.0000 -830.0000 |
118-10-5 Cinchonine D-CINCHONINE
An alkaloid derived from the bark of the cinchona tree.
It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.
Cinchonine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.
It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
Cinchonine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
Cinchonine Basic information | |
Product Name: | Cinchonine |
Synonyms: |
D-CINCHONINE;(+)-CINCHONINE;CINCHONINE;CINCHONAN-9-OL,(9S)-; (+)-cinconine;(8r,9s)-cinchonine;(9s)-cinchonan-9-o;(9S)-Cinchonan-9-ol |
CAS: | 118-10-5 |
MF: | C19H22N2O |
MW: | 294.39 |
EINECS: | 204-234-6 |
Product Categories: |
Quinoline Alkaloids;Quinolinecarboxylic Acids, etc.;Quinolines;Synthetic Organic Chemistry; Asymmetric Synthesis;Chiral Resolution Reagents;Chiral Resolving ReagentsChiral Catalysts, Ligands, and Reagents;Cinchona Alkaloids;Privileged Ligands and Complexes;Aromatics; Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Miscellaneous Natural Products;chiral;Alkaloids;Biochemistry;for Resolution of Acids;Optical Resolution;API; DOBUTREX |
Mol File: | 118-10-5.mol |
Cinchonine Chemical Properties | |
Melting point | 260-263 °C |
alpha | 224 º (c=0.5, alcohol) |
Boiling point | 436.16°C (rough estimate) |
density | 1.0863 (rough estimate) |
refractive index | 223 ° (C=0.5, EtOH) |
storage temp. | Store below +30°C. |
solubility | 0.25g/l |
form | Micro-Crystalline Powder |
pka | 5.85, 9.92(at 25℃) |
color | White to light beige |
PH | 9.0 (0.25g/l, H2O, 20℃)(as aqueous solution) |
optical activity | [α]23/D +228°, c = 0.5 in ethanol |
Water Solubility | Insoluble |
Sensitive | Light Sensitive |
Merck | 142287 |
BRN | 89689 |
Stability: | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.
Cinchonine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.
It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
Cinchonine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
CAS NO:6147-66-6
CAS NO:124-02-7
CAS NO:83-07-8
CAS NO:76-03-9
CAS NO:145-13-1
CAS NO:819-79-4
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View