CasNo.119413-54-6,Hycamtin,Topotecan hydrochloride,cas:119413-54-6,(119413-54-6) Suppliers

1 Gram	FOB Price:USD 6880.0000 -6894.0000

Min.Order :1 Gram
Purity: 99%
Payment Terms : L/C,D/A,D/P,T/T,

Keywords

119413-54-6 Topotecan hydrochloride Hycamtin

Quick Details

Appearance:white powder
Application:Topitaikang Hydrochloride is a third generation of anthophylline drugs with strong anticancer activity, which has been discovered after hydroxysycamine. The results showed that the myelosuppression wa
PackAge: according to customers' requirements
ProductionCapacity:10000|Metric Ton|Month
Storage:Refrigerator
Transportation:Air, sea, land transport

Superiority:

Topotecan Hydrochloride (Topotecan HCl) is a semi-synthetic derivative of camptothecin. Camptothecin is a natural product extracted from the bark of the tree Camptotheca acuminata. Topoisomerase-I is a nuclear enzyme that relieves torsional strain in DNA by opening single strand breaks. Once topoisomerase-I creates a single strand break, the DNA can rotate in front of the advancing replication fork. Topotecan intercalates between DNA bases. This intercalation disrupts the DNA deplication machinery when it reaches a site where topotecan is intercalated.
Topotecan is an antineoplastic agent used to treat small cell lung cancer, and certain cancers of the ovary.
Topotecan is also used to treat relapse of small cell lung cancer that initially responded to other drugs. Increases in survival times have been observed in patients treated with topotecan compared to control populations treated with paclitaxel.

Details:

Introduction:

1.English name:Topotecan
2.Molecular Formula:C23H23N3O5
3.Molecular Weight:421.4458
4.CAS Registry Number:123948-87-8
5.Quality:98%
6.Density:1.49g/cm3
7.Boiling point:782.9°C at 760 mmHg
8.Refractive index:1.733 Flash point:427.3°C

9.Vapour Pressur:8.13E-26mmHg at 25°C

Function:

Used for small cell lung cancer and metastatic ovarian cancer after failure of primary and middle chemotherapy.
1.Topological treatment of first-line chemotherapeutic sensitive recurrent small cell lung cancer is similar or better, and good tolerance, easy to take, low hematological toxicity;
2. Topological tiikang oral formulation as the second-line treatment of ovarian cancer has a good effect, convenient to take, low hematologic toxicity and good tolerance;
3.Oral topotikang capsule combined with cisplatin is a safe and effective drug for the treatment of widespread small cell lung cancer.

All Key Manufacturers and Suppliers of Baoji Guokang have routine inspections to ensure they are in compliance with the standards set in place during the original Supplier Assessment Inspection.

Production Inspection Process:

Our Group service includes regular and thorough inspections throughout the manufacturing process, eliminating the need to employ additional quality control inspectors.

- Raw material before any production begins

- Pre-production samples to ensure specifications are being met

- In-process to confirm that standards are maintained

- Pre-shipping to ensure that the product arrives to the customer exactly as expected and is packaged

correctly to prevent any damage in transit.

We can help operating split shipments, meeting the factory minimum quantity but ship them in 2 or 3 shipments with required gaps among. This allows you to move stock through your business without taking up space and capital.

We will arrange the subsequent shipments from our factory to your warehouse.

We can consolidate your small orders from multiple factories, delivering all at the same time to you or your customers,using the most cost-effective route available. At the time of order placement, we will offer details to you about the volume of each component part and what size container will be used.

We can offer the complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.

Delivery can be offered.

- Utilizing your own freight-forwarder

- FOB to a port in China

- CIF to a port near you

Whether you have your own freight-forwarder or you would like to organize shipment; whether you require delivery FOB in China or CIF to a port near you, we are glad to quote and supply whichever way you choose. Please feel free to discuss all options with us.