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100986-85-4 Levofloxacin hydrochloride Lelofloxacin
Levofloxacin, sold under the trade names Levaquin among others, is an antibiotic. It is used to treat a number of bacterial infections including acute bacterial sinusitis, pneumonia, urinary tract infections, chronic prostatitis, and some types of gastroenteritis. Along with other antibiotics it may be used to treat tuberculosis, meningitis, or pelvic inflammatory disease. It is available by mouth, intravenously,and in eye drop form.
Common side effects include nausea, diarrhea, and trouble sleeping. Serious side effects may include tendon rupture, tendon inflammation, seizures, psychosis, and potentially permanent peripheral nerve damage. Tendon damage may appear months after treatment is completed. People may also sunburn more easily. In people with myasthenia gravis, muscle weakness and breathing problems may worsen.The risk of use during pregnancy is low and it is probably okay during breastfeeding. Levofloxacin is a broad-spectrum antibiotic of the fluoroquinolone drug class.It usually results in death of the bacteria. It is the left sided isomer of the medication ofloxacin.
Product Name: |
Levofloxacin |
Appearance : |
white powder |
|
CAS: |
100986-85-4 |
Molecular formula: |
C18H20FN3O4 |
|
Molecular weight : |
490.6156 |
EINECS No: |
202-713-4 | |
Synonyms: |
LVFX; |
Levofloxacin is a broad spectrum antibiotic of thefluoroquinolone drug class,and the levo isomer of its predecessor ofloxacin.
Levofloxacin is an antibiotic that is used for treating bacterial infections. Many common infections in humans are caused by bacteria. Bacteria can grow and multiply, infecting different parts of the body. Drugs that control and eradicate these bacteria are called antibiotics. Levofloxacin is an antibiotic that stops multiplication of bacteria by preventing the reproduction and repair of their genetic material, DNA. It is in a class of antibiotics called fluoroquinolones, a class that includes ciprofloxacin (Cipro), norfloxacin (Noroxin), ofloxacin (Floxin), trovafloxacin (Trovan), and lomefloxacin (Maxaquin).
Application:
Levofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. Like all quinolones, it functions by inhibiting the two type II topoisomerase enzymes, ie DNA gyrase and topoisomerase IV. Topoisomerase IV is necessary to separate DNA With the DNA of the cell, the process is stopped, and the bacterium cannot divide. DNA gyrase, on the other hand, is responsible for supercoiling the DNA, so that it will Fit in the newly formed cells. Both mechanisms amount to killing the bacterium. In this way, levofloxacci acts as a bactericide.
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