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34580-14-8 Ketotifen fumarate zaditen
Ketotifen fumarate, a Histamine H1 receptor antagonist, has been noted to inhibit histamine release from lymphocytes and monocytes at 0.1-10 μM. Ketotifen has demonstrated inhibiting characteristics against mast cell growth, therefore reducing myofibroblast hyperplasia. This compound has displayed induction capacities in primary necrosis of interleukin-5-treated eosinophils. Ketotifen fumarate is an inhibitor of PDE.
Product Name: Ketotifen fumarate
English name: 10- (1-methylpiperidin-4-ylidene) -5H-benzo [1,2] cyclohepta [3,4-b] thiophen-4-one
CAS Number: 34580-13-7
Molecular formula: C19H19NOS
Molecular weight: 309.42500
Ketotifen fumarate is a first-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt with fumaric acid, ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis.In its oral form, it is used to prevent asthma attacks or Anaphylaxis, as well as various mast cell, allergic-type disorders.
Ketotifen fumarate is a first-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt with fumaric acid, ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis.In its oral form, it is used to prevent asthma attacks or Anaphylaxis, as well as various mast cell, allergic-type disorders.
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