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138-59-0 Shikimic acid API
Shikimicacid oxalate is found in the dried fruit of Illicium lanceolatum A. C. Smith, an evergreen shrub of Magnoliaceae. Star anise is an evergreen tree growing in moist, warm and semi cloudy environment. It can be as high as 20 meters. It is mainly distributed in the south of China. Bark gray to reddish brown. Shikimicacid shikimic acid is found in the dried fruit of Illicium lanceolatum A.C. Smith, an evergreen shrub of Magnoliaceae. The height of the plant is 3 m~8 m, the leaves are leathery, 1~2 axillary; the apex has long and curved tips; the seeds are light brown and lustrous. Florescence May, fruit period 9 to October. Globally, 90% of anise is produced in China, mainly in the loose mountain areas of Fujian, Guangdong, Guangxi, Yunnan and Guizhou provinces. In addition to plants, shikimic acid is also widely found in microorganisms, which can be extracted by microbial fermentation. Oxalic acid inhibits platelet aggregation, arteriovenous thrombosis and cerebral thrombosis by affecting arachidonic acid metabolism. Shikimic acid has anti-inflammatory and analgesic effects. Shikimic acid can also be used as an intermediate of antiviral and anticancer drugs. Shikimic acid is often used as a pharmaceutical intermediate. It is irritating. Please do not use it directly.
Name |
Shikimic acid |
Synonyms |
(3R,4S,5R)-(-)-3,4,5-Trihydroxy-1-cyclohexenecarboxylic acid; 3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid |
Molecular Formula |
C7H10O5 |
Molecular Weight |
174.15 |
CAS Registry Number |
138-59-0 |
EINECS |
205-334-2 |
alpha |
-180 º (c=4, H2O 25 ºC) |
Water solubility |
18 g/100 mL (20 ºC) |
1. Shikimic acid effected by arachidonic acid.
2. Shikimic acid acts as anti-inflammatory ,analgesic.
3. Shikimic acid is the drug intermediates of anti-cancer and anti-virus.
4. Shikimic acid is also the basis raw materials of combating avian flu.
5.Shikimic acid can inhibit the concentrating of the blood platelets,inhibit arterial,venous thrombosis and cerebral thrombosis.
Application:
1. It is a kind of anti-cancer drug and also a synthetic material of dioxin, glyoxalase inhibitor and other anti-cancer drugs.
2. Shikimic acid is a monomer compound extracted from star anise, a traditional Chinese medicine. It has anti-inflammatory and analgesic effects and is an intermediate of anticancer drugs.
3. shikimic acid is a key precursor for the synthesis of many alkaloids, aromatic amino acids, indole derivatives and chiral drugs.
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