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1197-18-8 Amstat Tranexamic acid
Tranexamic acid is a synthetic derivative of the amino acid lysine.Tranexamic acid (commonly marketed in tablet form as Lysteda and in IV form as Cyklokapron in the U.S. and as Transamin,Transcam in Asia, and Espercil in South America) is often prescribed for excessive bleeding.
Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule responsible for the degradation of fibrin. Fibrin is the basic framework for the formation of a blood clot in hemostasis.Tranexamic acid has roughly 8 times the antifibrinolytic activity of an older analogue, ε-aminocaproic acid.
CAS No.1197-18-8
EINECS No.214-818-2
Molecular formula: C8H15NO2
Molecular weight: 157.21
Appearance: White or almost white, crystalline powder
Tranexamic acid (TXA) is a medication used to treat or prevent excessive blood loss from trauma, surgery, and in various medical conditions including hemophilia and heavy menstrual bleeding. It comes in oral and intravenous forms.
Side effects are uncommon and include gastrointestinal effects, dizziness, fatigue, headache, and hypersensitivity reactions. The medication needs to be used cautiously in people with kidney disease and who are at a high risk for blood clots. Tranexamic is safe to use in pregnant women. However, caution should be used in lactating women. It is an antifibrinolytic.
It was discovered in 1962 by Utako Okamoto and has been on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
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