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Butenafine hydrochloride Butenafine HCl Butenafine Hydrochloride Butenafine Hydrochloride Butenafine HCl Butenafine Hydrochloride
Butenafine hydrochloride is an odorless white crystalline powder that is freely soluble in methanol, ethanol, and chloroform, and slightly soluble in water.
Like the allylamine antifungals, butenafine works by inhibiting the synthesis of ergosterol by inhibiting squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes. Lacking ergosterol, the cell membranes increase in permeability, allowing their contents to leak out.
Butenafine HCl Butenafine Hydrochloride
Butenafine HCl Butenafine Hydrochloride
Systematic (IUPAC) name | |
---|---|
[(4-tert-butylphenyl)methyl](methyl)(naphthalen-1-ylmethyl)amine | |
Clinical data | |
Trade names | Mentax |
AHFS/Drugs.com | monograph |
Pregnancy cat. | |
Legal status | |
Routes | topical |
Pharmacokinetic data | |
Metabolism | Hepatic |
Half-life | 35-100 hours |
Identifiers | |
CAS number | 101828-21-1 |
ATC code | D01AE23 |
PubChem | CID 2484 |
DrugBank | DB01091 |
ChemSpider | 2390 |
UNII | 91Y494NL0X |
KEGG | D07596 |
ChEBI | CHEBI:3238 |
ChEMBL | CHEMBL990 |
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