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Buy Lansoprazole 103577-45-3 103577-45-3 Lansoprazole producer 103577-45-3 in China
Name | lansoprazole |
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Synonym | More Synonyms |
Description | Lansoprazole(AG 1749) is a proton pump inhibitor which prevents the stomach from producing acid.Target: Proton PumpLansoprazole, a substituted benzimidizole proton pump inhibitor, on pharmacokinetics and metabolism of theophylline has been studied in healthy adults given oral lansoprazole 30 mg once daily for 11 days. On Days 4 and 11 of 300 mg aminophylline was simultaneously administered orally and blood samples for theophylline analysis were taken over 24 h [1]. Patients in the lansoprazole group were significantly less likely to have a recurrence of ulcer complications than patients in the placebo group (P=0.008). There was no significant difference in mortality between the two groups [2]. lansoprazole (AG-1749) and omeprazole, were found to have significant activities against this organism. The activity of lansoprazole was comparable to that of bismuth citrate, with MICs ranging from 3.13 to 12.5 micrograms/ml, and fourfold more potent than that of omeprazole [3]. Clinical indications: Duodenal ulcer; Esophagitis; Gastroesophageal reflux; Gastrointestinal disease; Helicobacter pylori infection; Peptic ulcer; Stomach ulcer; Ulcer; Zollinger-Ellison syndromeFDA Approved Date: May 10, 1995Toxicity: Symptoms of overdose include abdominal pain, nausea and diarrhea. | ||||||||||||
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Related Catalog | |||||||||||||
Solvent |
In Vitro:
DMSO : 100 mg/mL (270.74 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble) In Vivo: 1.Add each solvent one by one: 10% DMSO 90% corn oil Solubility: ≥ 2.5 mg/mL (6.77 mM); Clear solution 2.Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% saline Solubility: ≥ 2.5 mg/mL (6.77 mM); Clear solution |
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Solubility |
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Storage |
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Shipping | Room temperature in continental US; may vary elsewhere | ||||||||||||
SMILES | O=S(C1=NC2=CC=CC=C2N1)CC3=NC=CC(OCC(F)(F)F)=C3C | ||||||||||||
References | |||||||||||||
Related Molecules | Bafilomycin A1 | omeprazole | Vonoprazan fumarate | Zinc Pyrithione | (R)-Lansoprazole | Ilaprazole | AZD0865 | Soraprazan | bamaquimast | Esomeprazole | Esomeprazole magnesium| Chebulinic acid | Picoprazole | SKF96067 | Pumaprazole | ||||||||||||
Related Doc |
*The above documents are provided by Medchemexpress and are for scientific research only. |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 555.8±60.0 °C at 760 mmHg |
Melting Point | 178-182°C dec. |
Molecular Formula | C16H14F3N3O2S |
Molecular Weight | 369.362 |
Flash Point | 289.9±32.9 °C |
Exact Mass | 369.075867 |
PSA | 87.08000 |
LogP | 2.76 |
Vapour Pressure | 0.0±1.5 mmHg at 25°C |
Index of Refraction | 1.635 |
Storage condition | 2-8°C |
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Basic information
Product Name: |
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Synonyms: |
(2-Nitro-1-propenyl)benzene;(2-Nitropropenyl)benzene;[(1E)-2-Nitro-1-propenyl]benzene;1-(2-nitropropenyl)-benzen;1-(2-Nitropropenyl)benzene;1-Phenyl-2-nitro-1-propene;1-Phenyl-2-nitro-propylen-(1,2);2-Nitro-1-phenyl-1-propene |
CAS: |
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MF: |
C9H9NO2 |
MW: |
163.17 |
Product Categories: |
Aromatic Hydrocarbons (substituted) & Derivatives;Acyclic;Alkenes;Organic Building Blocks;Building Blocks;Chemical Synthesis;Organic Building Blocks;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals |
Mol File: |
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Chemical Properties |
melting point |
63-65 °C(lit.) |
boiling point |
263 °C at 760 mmHg |
density |
1.141 g/cm3 |
vapor pressure |
0.0172 mmHg at 25°C |
flashing point |
115.7 °C |
storage temp. |
2-8°C |
Usage And Synthesis |
Chemical Properties |
Yellow crystalline powder |
Usage |
Styrene derivative, with herbicide and antibacterial properties. |
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