CasNo.866460-33-5,2-(2-(1-naphthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetic acid,(866460-33-5) Suppliers

10 Gram	FOB Price:USD 9.0000 -10.0000

Min.Order :10 Gram
Purity: 98%
Payment Terms : L/C,D/A,D/P,T/T,

Keywords

2-(2-(1-naphthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetic acid 866460-33-5 2-(2-(1-phthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetic acid

Quick Details

Appearance:white powder
Application:Medical intermediates
PackAge: according to customers' requirements
ProductionCapacity:10000|Metric Ton|Month
Storage:2-8°C
Transportation:Air, sea, land transport

Superiority:

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present, our customers have spread all over the world, we have rich Transportation experience, we aim to serve customers, to help customers, solve problems for customers. Look forward to working with you!

Details:

Introduction:

Setipiprant (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by Actelion which acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2). It was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma, but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced airway responses in asthmatic patients, it failed to show sufficient advantages over existing drugs and was discontinued from further development in this application.

However, following the discovery in 2012 that the prostaglandin D2 receptor (DP/PGD2) is expressed at high levels in the scalp of men affected by male pattern baldness, the rights to setipiprant were acquired by Kythera with a view to potentially developing this drug as a novel treatment for baldness, with a previously unexploited mechanism of action. While it is too early to tell whether setipiprant will be an effective treatment for this condition, the favorable pharmacokinetics and relative lack of side effects seen in earlier clinical trials mean that fresh clinical trials for this new application can be conducted fairly quickly.

A phase 2A study is underway to evaluate the safety, tolerability, and efficacy of oral setipiprant relative to a placebo and the active comparator, finasteride, in 18 to 41 years old males with androgenetic alopecia.

Function：

Setipiprant is the drug for the treatment of hair loss dwindled, perhaps due more to commercial potential and chemical stability reasons than efficacy as the later studies of Setipiprant have focused on different chemical forms of the drug and combining it with various nanoparticles to enhance delivery. phrenics.

All Key Manufacturers and Suppliers of Baoji Guokang have routine inspections to ensure they are in compliance with the standards set in place during the original Supplier Assessment Inspection.

Production Inspection Process:

Our Group service includes regular and thorough inspections throughout the manufacturing process, eliminating the need to employ additional quality control inspectors.

- Raw material before any production begins

- Pre-production samples to ensure specifications are being met

- In-process to confirm that standards are maintained

- Pre-shipping to ensure that the product arrives to the customer exactly as expected and is packaged

correctly to prevent any damage in transit.

We can help operating split shipments, meeting the factory minimum quantity but ship them in 2 or 3 shipments with required gaps among. This allows you to move stock through your business without taking up space and capital.

We will arrange the subsequent shipments from our factory to your warehouse.

We can consolidate your small orders from multiple factories, delivering all at the same time to you or your customers,using the most cost-effective route available. At the time of order placement, we will offer details to you about the volume of each component part and what size container will be used.

We can offer the complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.

Delivery can be offered.

- Utilizing your own freight-forwarder

- FOB to a port in China

- CIF to a port near you

Whether you have your own freight-forwarder or you would like to organize shipment; whether you require delivery FOB in China or CIF to a port near you, we are glad to quote and supply whichever way you choose. Please feel free to discuss all options with us.