dabigatran 211914-51-1 C25H25N7O3
Dabigatran Basic information |
Product Name: | Dabigatran |
Synonyms: | β-Alanine,N-[[2-[[[4-(aMinoiMinoMethyl)phenyl]aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-;3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid;3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid Dabigatran (BIBR 953);Dabigatran Impurity b;Dabigatran (Acid);3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic;Dabigatran(BIB-953;3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Met |
CAS: | 211914-51-1 |
MF: | C25H25N7O3 |
MW: | 0 |
EINECS: | |
Product Categories: | -;Other APIs;Inhibitors;benzimidazol;Dabigatran impurity;Aromatics;Inhibitor;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Bases & Related Reagents;Heterocycles |
Mol File: | 211914-51-1.mol |
Dabigatran Chemical Properties |
Melting point | 268-272°C |
storage temp. | Refrigerator, Under Inert Atmosphere |
Dabigatran Usage And Synthesis |
Chemical Properties | Tan Solid |
Uses | BIBR 953 (Dabigatran, Pradaxa) is potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM |
Uses | Nonpeptide, direct thrombin inhibitor. Antithrombotic. |
Definition | ChEBI: An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amoino group of N-pyridin-2-yl-b ta-alanine. The active metabolite of the prodrug dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism. |
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