Isobutaneboronic acid 84110-40-7 C4H11BO2
Isobutaneboronic acid Basic information |
Product Name: | Isobutaneboronic acid |
Synonyms: | (2-Methylpropyl)boronic acid >=95.0%;Isobutylboronic Acid, 95+%;Isobutaneboronic acid (2-Methylpropyl)boronic acid;Isobutylboronic Acid (contains varying a…;Boronic acid, B-(2-methylpropyl)-;Bortezomib Impurity 31;RARECHEM AH PB 0258;2-METHYL-1-PROPYLBORONIC ACID |
CAS: | 84110-40-7 |
MF: | C4H11BO2 |
MW: | 101.94 |
EINECS: | 617-531-4 |
Product Categories: | -;Boron, Nitrile, Thio,& TM-Cpds;Boronic acids;Organoborons;Alkyl;B (Classes of Boron Compounds);CHIRAL CHEMICALS |
Mol File: | 84110-40-7.mol |
Isobutaneboronic acid Chemical Properties |
Melting point | 108-111 °C(lit.) |
storage temp. | 0-6°C |
form | Crystalline Powder or Flakes |
color | White to cream |
CAS DataBase Reference | 84110-40-7(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 37/39-26 |
WGK Germany | 3 |
Hazard Note | Irritant |
HazardClass | IRRITANT |
HS Code | 29319090 |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
ACROS | English |
Isobutaneboronic acid Usage And Synthesis |
Description | Isobutaneboronic acid is also known as isobutylboronic acid. Isobutaneboronic acid has been used to synthesize potent and selective dipeptidyl boronic acid proteasome inhibitors, which are promising therapeutics to treat cancer and inflammatory diseases.1 |
Reference | J. Adams, M. Behnke, S. Chen, A. A. Cruickshank, L. R. Dick, L. Grenier, J. M. Klunder, Y. Ma, L. Plamondon, R. L. Stein, Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acids, Bioorganic & Medicinal Chemistry Letters, 1998, vol. 8, pp. 333-338 |
Chemical Properties | white flake |
Uses | suzuki reaction |
Uses | 2-Methylpropylboronic Acid is used in the preparation of isocoumarin analogs as inhibitors of γ-secretase cleavage. Also used in the preparation of peptide boronc acid. |
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