Teneligliptin

Teneligliptin
Teneligliptin
Teneligliptin

Teneligliptin

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: 99（%）
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Teneligliptin 760937-92-6 C22H30N6OS

Quick Details

  • Appearance:powder
  • Application:760937-92-6
  • PackAge:25KG/Cardboard bucket or as required
  • ProductionCapacity:5|Metric Ton|Day
  • Storage:keep in dry and cool condition
  • Transportation:by sea or by air

Superiority:

Teneligliptin Basic information
Product Name: Teneligliptin
Synonyms: API (Teneligliptin free base);teneligliptin;[(2S,4S)-4-[4-(5-methyl-2-phenylpyrazol-3-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone;3-[[(2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]carbonyl]thiazolidine;Methanone,[(2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinyl-;Teneligptin WS
CAS: 760937-92-6
MF: C22H30N6OS
MW: 426.58
EINECS:  
Product Categories: -
Mol File: 760937-92-6.mol
Teneligliptin Structure
 
Teneligliptin Chemical Properties
density  1.38
 
Safety Information
MSDS Information
 
 
Teneligliptin Usage And Synthesis
Description Teneligliptin was approved in September 2012 in Japan for the treatment of patients with Type 2 diabetes mellitus (T2DM). Teneligliptin is a member of the dipeptidyl peptidase 4 (DPP-4) inhibitor class of antidiabetes agents. DPP-4 is an enzyme that degrades GLP-1, a 30-amino acid peptide that is secreted in response to food intake. GLP-1 stimulates insulin secretion and inhibits glucagon secretion, which leads to lower levels of plasma glucose. Teneligliptin is one of a growing numbers of DPP-4 inhibitors to be approved worldwide. The discovery of teneligliptin was guided by structure-based design, with a key element being binding of the phenyl group in the S2 pocket, which not only increases potency for DPP-4, but also improves selectivity versus DPP-8 and DPP- 9. Teneligliptin is a potent inhibitor of DPP-4 in the enzyme inhibition assay (IC50=0.37 nM).
Originator Mitsubishi Tanabe Pharma (Japan)
Brand name Tenelia

 

Details:

Changzhou Xuanming Chemical Co., Ltd. is dedicated to the technology development, manufacturing, import and export chemicals, which are specialized in pharmaceutical intermediates, pesticide intermediate, industry of fine chemicals and custom synthesis. Now, we enjoy good reputation among customers and take favorable market share in domestic and at abroad.

Changzhou Xuanming Chemical CO., LTD is located in Northern Jiangshu Industry Park, we have modern manufacture bases and some laboratories, which can supply the key intermediate for your projects, and short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard. We have been abided by “treat technology as first, quality as basis, customers as God, and be honest and sincere”. It is our final aim to provide environmental and high technological products and meet customers’ requirements according to keep effors on developing new chemical fields.

Changzhou Xuanming Chemical CO., LTD promises to help you with heart and soul.

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