Chlorhexidine Acetate 56-95-1 C24H34Cl2N10O2
Chlorhexidine Diacetate Basic information |
Product Name: | Chlorhexidine Diacetate |
Synonyms: | Chlorhexidine Acetate (200 mg);Chlorhexidine Acatate;1,6-Bis(4-chlorophenyldiguanidino)hexane Diacetate;1,1'CB2771984;Chlorhexidine acetate (chlorhexidine acetate);Chlorhexidine di;1,1’-hexamethylenebis(5-(p-chlorophenyl)-biguaniddiacetate |
CAS: | 56-95-1 |
MF: | C26H38Cl2N10O4 |
MW: | 625.55 |
EINECS: | 200-302-4 |
Product Categories: | Pharmaceutical raw materials;disinfectant;-;Organics |
Mol File: | 56-95-1.mol |
Chlorhexidine Diacetate Chemical Properties |
Melting point | 153-156°C |
storage temp. | room temp |
solubility | H2O: 15 mg/mL, clear |
form | neat |
Water Solubility | 1.9 g/100 mL (20 ºC) |
Merck | 14,2091 |
InChIKey | GHXZTYHSJHQHIJ-UHFFFAOYSA-N |
CAS DataBase Reference | 56-95-1(CAS DataBase Reference) |
EPA Substance Registry System | 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)- 3,12-diimino-, diacetate(56-95-1) |
Safety Information |
Hazard Codes | Xn,Xi,N |
Risk Statements | 22-43-36/37/38-50/53 |
Safety Statements | 36/37-36-26-61-60 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | 3 |
RTECS | DU1930000 |
F | 8-10 |
HazardClass | 9 |
PackingGroup | III |
Toxicity | LD50 orally in mice: 2 g/kg (Davies) |
Chlorhexidine Diacetate Usage And Synthesis |
Chemical Properties | Chlorhexidine Diacetate is white or almost white, microcrystalline powder |
Uses | Chlorhexidine Diacetate is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. Chlorhexidine is a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria. It has both bactericidal and bacteriostatic mechanisms of action. Aqueous solutions of chlorhexidine are most stable within the pH range of 5-8. Above pH 8.0 chlorhexidine base is precipitated and in more acid conditions there is gradual deterioration of activity because the compound is less stable. Chlorhexidine is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs. |
Chlorhexidine Diacetate Preparation Products And Raw materials |
Raw materials | 4-Chloroaniline |
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