BleoMycin sulfate

BleoMycin sulfate
BleoMycin sulfate
BleoMycin sulfate

BleoMycin sulfate

Min.Order / FOB Price:Get Latest Price

1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 99（%）
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

BleoMycin sulfate 9041-93-4 C110H168N34O46S7

Quick Details

  • Appearance:powder
  • Application: For pharmaceutical
  • PackAge:25KG/Cardboard bucket or as required
  • ProductionCapacity:5|Metric Ton|Month
  • Storage:Store in dry, dark and ventilated place
  • Transportation:by air or by sea

Superiority:

 

Bleomycin sulfate Basic information
Product Name: Bleomycin sulfate
Synonyms: BLEOMYCIN SULFATE CELL CULTURE TESTED;BLEOMYCIN SULFATE, BPC;BLEOMYCIN SULFATE FROM STREPTOMYCES VERT ICILLUS, LYOPH.;BLEOMYCIN SULFATE FROM STREPTOMYCES VERTICILLUS 0 TO 5 °C;Blocamicina;BLEMOYCIN SULFATE;3-[[2-[2-[2-[2-[4-[2-[6-Amino-2-[1-(2-amino-2-carbamoyl-ethyl)amino-2-carbamoyl-ethyl]-5-methyl-pyrimidin-4-yl]carbonylamino-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(3H-imidazol-4-yl)propanoyl]amino-3-hydroxy-2-methyl-pentanoyl]amino-3-hydroxy-butanoyl]aminoethyl]-1,3-thiazol-4-yl]-1,3-thiazol-4-yl]carbonylamino]propyl-dimethyl-sulfonium hydrogen sulfate;Bleomycin Sulfate, Blenoxane
CAS: 9041-93-4
MF: C110H168N34O46S7
MW: 2927.17
EINECS: 232-925-2
Product Categories: Active Pharmaceutical Ingredients;UVCBs-biological;Intermediates & Fine Chemicals;Pharmaceuticals;Carbohydrates & Derivatives;Sulfur & Selenium Compounds;API;Inhibitors;-;BLENOXANE;antibiotic
Mol File: 9041-93-4.mol
Bleomycin sulfate Structure
 
Bleomycin sulfate Chemical Properties
Melting point  200-204°C (dec.)
storage temp.  2-8°C
solubility  H2O: 20 mg/mL
form  powder
color  white
Water Solubility  Soluble in water or DMSO
Merck  14,1318
CAS DataBase Reference 9041-93-4(CAS DataBase Reference)
 
Safety Information
Hazard Codes  T,Xi
Risk Statements  46-40-36/37/38-63
Safety Statements  53-36/37-45-36-26
WGK Germany  3
RTECS  EC5991990
F  10
 
 
Bleomycin sulfate Usage And Synthesis
Chemical Properties White Powder
Uses A group of related glycopeptide antibiotics. Bleomycin A2 is the main component of the bleomycin employed clinically. Antineoplastic
Uses Bleomycin is a complex of 11 glycopeptide antitumour antibiotics originally isolated from Streptomyces verticillus in 1972. The dominant components of the complex are bleomycin A2 and B2, which typically represent >90% of the total weight . Bleomycins have found clinical application in the treatment of a range of tumours. Bleomycins act by intercalation of DNA and RNA. In the presence of oxygen and metal ions, notably copper and iron, bleomycins form a pseudo-enzyme that induces DNA cleavage.
Uses Bleomycin is a complex of 11 glycopeptide antitumor antibiotics originally isolated from Streptomyces verticillus in 1972. The dominant components of the complex are bleomycin A2 and B2, which typically represent >90% of the total weight. Bleomycins have found clinical application in the treatment of a range of tumors. Bleomycins act by intercalation of DNA and RNA. In the presence of oxygen and metal ions, notably copper and iron, bleomycins form a pseudo-enzyme that induces DNA cleavage.
Brand name Blenoxane (Bristol-Myers Squibb).
General Description Bleomycin occurs as a white powder and is available in 15-and 30-U vials for reconstitution in water. It may be givenintravenously, intramuscularly, or subcutaneously. It is used in the treatment of squamous cell carcinoma of the headneck, cervix, penis, and vulva. It is also used in Hodgkin’sand non-Hodgkin’s lymphoma as well as testicular carcinoma.Unlabeled uses include the treatment of mycosis fungoides,osteosarcoma, and AIDS-related Kaposi sarcoma.
Veterinary Drugs and Treatments Bleomycin has occasionally been used as adjunctive treatment of lymphomas, squamous cell carcinomas, teratomas, and nonfunctional thyroid tumors in both dogs and cats. Recent work has demonstrated that bleomycin may be promising for intralesional treatment for a variety of localized tumors with or without concomitant electropermeabilization.
 
Bleomycin sulfate Preparation Products And Raw materials
Preparation Products PEPLOMYCIN
Raw materials Potassium dihydrogen phosphate-->Zinc sulphate-->Disodium edetate dihydrate-->streptomyces avermifilis-->Dithizone-->Cation exchange resin,weak acidic acrylic acid

 

Details:

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Changzhou Xuanming Chemical CO., LTD is located in Northern Jiangshu Industry Park, we have modern manufacture bases and some laboratories, which can supply the key intermediate for your projects, and short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard. We have been abided by “treat technology as first, quality as basis, customers as God, and be honest and sincere”. It is our final aim to provide environmental and high technological products and meet customers’ requirements according to keep effors on developing new chemical fields.

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