kojic acid 5-Hydroxy-2-(hydroxymethyl)-4-pyrone 3-hydroxy-6-hydroxymethyl-4H-pyran-4-one
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Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and to treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It inhibits activation of T cells and B cells by reducing the production of interleukin-2 (IL-2).
Product name : Rapamycin/Sirolimus
CAS 53123-88-9
Appearance : white crystalline powder
Purity :99% min
Specification of Rapamycin
Item |
Specifications |
Results |
Description |
off-white to yellow crystalline powder |
Complies |
Identification |
The IR spectrum of Potassium Bromide preparation of the sample exhibits maxima at the same wavelengths as that of a similar preparation of in-house reference standard |
Complies
|
The UV spectrum of 95% Ethanol preparation of the sample exhibits maxima at 267nm, 277nm, 288nm that of similar preparation of in-house reference standard. |
Complies |
|
The retention times of the peaks for the Trans- and Cis-stereoisomers in the chromatogram of Assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the Assay |
Complies |
|
Loss on drying |
≤0.5% |
0.16% |
Heavy metal |
≤0.002% |
Complies |
Total impurity |
≤2.0% |
0.76% |
Single impurity |
≤1.0% |
0.67% |
Cis-stereoisomer of Sirolimus |
≤5.0% |
2.4% |
Assay |
≥98.0% |
99.2% |
Conclusion |
The production complies with enterprise standard |
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