541-91-3 C16H30O (3R)-3α-Methylcyclopentadecanone
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Muscone Basic information |
Product Name: | Muscone |
Synonyms: | (3R)-3α-Methylcyclopentadecanone;(R)-(-)-Muscone;Muscone ,98%;Azedarachin;3-Methylcycl;Anti-MUSK (N-terminal) antibody produced in rabbit;Cyclopentadecanone, 3-methyl-;Cyclopentadecanone,3-methyl- |
CAS: | 541-91-3 |
MF: | C16H30O |
MW: | 238.41 |
EINECS: | 208-795-8 |
Product Categories: | -;NULL;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors |
Mol File: | 541-91-3.mol |
|
Muscone Chemical Properties |
Melting point | -15°C(lit.) |
Boiling point | 95°C/0.1mmHg(lit.) |
density | 0.9221 |
FEMA | 3434 | 3-METHYL-1-CYCLOPENTADECANONE |
refractive index | 1.4770 to 1.4810 |
RTECS | GY0950000 |
storage temp. | -20°C |
λmax | 285nm(EtOH)(lit.) |
JECFA Number | 1402 |
Merck | 14,6313 |
CAS DataBase Reference | 541-91-3(CAS DataBase Reference) |
NIST Chemistry Reference | Cyclopentadecanone, 3-methyl-(541-91-3) |
EPA Substance Registry System | Cyclopentadecanone, 3-methyl-(541-91-3) |
Safety Information |
TSCA | Yes |
Hazardous Substances Data | 541-91-3(Hazardous Substances Data) |
Muscone Usage And Synthesis |
Chemical Properties | Muscone is an odoriferous constituent of natural musk. It is a colorless liquid with very soft, sweet, musky odor and a perfumery, animal tonality.Numerous syntheses have been developed for its preparation including enantioselective methods to obtain the naturally occurring (3R)-enantiomer (l-muscone,. Because of its excellent stability, it can be used in awide range of products to give elegant,warm, animal notes. It is important for the reconstitution of naturalmusk. |
Chemical Properties | Musk is secreted exclusively by the male animals of Moschus moschiferus, a wild deer living in themountains of Nepal,Tibet, and Mongolia.Thelight yellow secretion with a salve consistency accumulates in the abdominal pouch and probably serves to attract the females. When the pouch is dried, the secretion solidifies to form a brittle, brown mass with a characteristic odor. Since several Moschus species occur, large variations exist in the quality and specifications of musk. Hunting of the animals has been prohibited; therefore, only small quantities ofmusk are occasionally offered at extremely high prices. In the United States and Europe, naturalmusk is no longer used as a fragrance ingredient. |
Chemical Properties | 3-Methyl-1-cyclopentadecanone has a soft, sweet, tenacious, musky odor. |
Chemical Properties | Colorless oily liquid |
Occurrence | Reported found in natural musk |
Preparation | From condensation of dodecamethyl-ene-α,ω-dimethylketone hexadecane. |
Aroma threshold values | Detection: 9.8 ppb |
Safety Profile | Low oral and skin contact toxicity. A skin irritant. A flammable liquid. When heated to decomposition it emits acrid smoke and irritating fumes. |
Muscone Preparation Products And Raw materials |
Raw materials | 1,3-BUTADIENE-->Semicarbazide-->Fragrance stabilizer-->Cyclopentadecanone |
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