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Product Description
Product Name:Olmesartan medoxomil
Cas No:144689-63-4
Molecular formula:C29H30N6O6
Molecular weight:558.585
Appearance:White crystalline powder
Assay: 99%
Olmesartan medoxomil is an angiotensin II receptor antagonist which has been used for the treatment of high blood pressure. It was developed by Sankyo in 1995, and is sold under the trade name Benicar Olmecip(Cipla)Olsar (Unichem Laboratories). An ester prodrug, it is completely and rapidly hydrolyzed to the active acid form, olmesartan .
Name |
Olmesartan medoxomil |
Synonyms |
Olmetec; CS-866; 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl ester |
Brand |
Salus |
Molecular Formula |
C29H30N6O6 |
Molecular Weight |
558.59 |
CAS Registry Number |
144689-63-4 |
Certificate of Analysis
Item |
Specification |
Result |
Appearance |
White or almost white crystalline powder |
white crystalline powder |
Identification IR HPLC UV |
Must conform to reference standard Must conform to reference standard Must conform to reference standard |
Conforms Conforms Conforms |
Water |
≤0.5% |
0.18% |
Residue On Ignition |
≤0.1% |
0.06% |
Heavy Metals |
≤0.001% |
<0.001% |
Related Compounds Olmesartan RRT 0.2 Olmesartan medoxoil related compound A. RRT 0.7 |
≤0.5% ≤0.1% |
0.2% 0.14% |
Assay |
98.5%~101.5% on the anhydrous and solvent-free basis |
99.5% |
Conclusion |
The results conforms with USP35 standards |
Function
Olmesartan medoxomil is antihypertensive drugs, for various high voltage has good curative effect
Its outstanding characteristic is a longer half-life, can effective control of blood pressure in a day, so take more convenient.
With a small dose, quick effect, antihypertensive effect is more strong and durable, low the incidence of adverse reactions of obvious advantages.
In addition, ogilvy sand temple of atherosclerosis, myocardial hypertrophy and heart failure, diabetes, kidney disease and so on all has a good effect.
Application
Olmesartan is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.The U.S. Food and Drug Administration (FDA) has determined that the benefits of Benicar continue to outweigh its potential risks when used for the treatment of patients with high blood pressure according to the drug label.
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