ALCAFTADINE 147084-10-4 C19H21N3O
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ALCAFTADINE Basic information |
Product Name: | ALCAFTADINE |
Synonyms: | ALCAFTADINE;6,11-Dihydro-11-(1-Methyl-4-piperidinylidene)-5H-iMidazo[2,1-b][3]benzazepine-3-carboxaldehyde;12-(1-Methylpiperidin-4-ylidene)-4,6,7,12-tetrahydrobenzo[d]pyriMido[1,2-a]azepine-3-carbaldehyde;5H-IMidazo[2,1-b][3]benzazepine-3-carboxaldehyde,6,11-dihydro-11-(1-Methyl-4-piperidinylidene)-;Alcaftadine, >=99%;R 89674;Alcaftadine (R89674) |
CAS: | 147084-10-4 |
MF: | C19H21N3O |
MW: | 307.395 |
EINECS: | 1308068-626-2 |
Product Categories: | Aromatics;Heterocycles;Pharmaceuticals;Inhibitors;Intermediates & Fine Chemicals |
Mol File: | 147084-10-4.mol |
ALCAFTADINE Chemical Properties |
density | 1.24 |
Safety Information |
ALCAFTADINE Usage And Synthesis |
Description | Alcaftadine, a histamine H1/H2 receptor antagonist, was approved in the United States in 2010 for the prevention of itching and redness associated with allergic conjunctivitis. Seasonal and perennial allergic conjunctivitis affects up to 40% of the population worldwide. There are numerous treatment options, with topical antihistamines being an effective therapy. Some of the primary symptoms and signs of allergic conjunctivitis are ocular itching and conjunctival redness. The pharmaceutical market for conjunctivitis is substantial and steadily increasing. |
Originator | Janssen Research Foundation (United States) |
Uses | Alcaftadine is a H1 histamine receptor antagonist. Alcaftadine is used to prevent eye irritation and treat the signs and symptoms of allergic conjunctivitis. |
Definition | ChEBI: An imidazobenzazepine that is 6,11-dihydro-5H-imidazo[2,1-b][3]benzazepine substituted at position 3 by a formyl group and at position 11 by a 1-methylpiperidin-4-ylidene group. An antihistamine used for treatment of allergi conjunctivitis. |
Brand name | LastacaftTM |
ALCAFTADINE Preparation Products And Raw materials |
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