Formoterol 73573-87-2 C19H24N2O4
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Formoterol Basic information |
Product Name: | Formoterol |
Synonyms: | rel-N-(2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-Methoxyphenyl)propan-2-yl)aMino)ethyl)phenyl)forMaMide;N-(2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide;1-nitrotridec-1-ene;n-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide;FORMOTEROL TARTRATE;FORMOTEROL;FORMOTEROL TARTARATE;FormoterolBase |
CAS: | 73573-87-2 |
MF: | C19H24N2O4 |
MW: | 344.4 |
EINECS: | |
Product Categories: | Other APIs;Inhibitors;(intermediates of formoterol ) |
Mol File: | 73573-87-2.mol |
Formoterol Chemical Properties |
solubility | DMSO: 20 mg/mL, soluble |
form | solid |
color | off-white |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 73573-87-2(CAS DataBase Reference) |
Safety Information |
WGK Germany | 3 |
Hazardous Substances Data | 73573-87-2(Hazardous Substances Data) |
Formoterol Usage And Synthesis |
Chemical Properties | solid |
Uses | Labeled Formoterol, intended for use as an internal standard for the quantification of Formoterol by GC- or LC-mass spectrometry. |
Definition | ChEBI: A phenylethanoloamine having 4-hydroxy and 3-formamido substituents on the phenyl ring and an N-(4-methoxyphenyl)propan-2-yl substituent. |
Brand name | Foradil (Novartis). |
General Description | Formoterol (Foradil) isalso a lipophilic (log P= 1.6) and long-acting β2-agonist. Ithas 3'-formylamino ( β-directing) and 4 OH groups on onephenyl ring and a lipophilic -directing N-isopropyl-pmethoxyphenylgroup on the nitrogen atom. Its long DOA(12 hours), which is comparable to that of salmeterol, hasbeen suggested to result from its association with the membranelipid bilayer, from which it gradually diffuses to provideprolonged stimulation of β2 receptors and its resistanceto MAO and COMT. Formoterol has a much faster onset ofaction than does salmeterol as result of its lower lipophilicity.Both of these long-acting drugs are used by inhalationand are recommended for maintenance treatment of asthma,usually in conjunction with an inhaled corticosteroid. |
Formoterol Preparation Products And Raw materials |
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