Brinzolamide 138890-62-7 Brinzolamide Brinzolamide
Brinzolamide is acarbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Systematic (IUPAC) name | |
---|---|
(5R)-5-ethylamino-3-(3-methoxypropyl)- 2,2-dioxo-2λ6,9-dithia- 3-azabicyclo[4.3.0]nona-7,10-diene- 8-sulfonamide |
|
Clinical data | |
Trade names | Azopt |
AHFS/Drugs.com | monograph |
MedlinePlus | a601233 |
Licence data | EMA:Link, US FDA:link |
Pregnancy cat. | C (US) |
Legal status | -only (US) |
Routes | Ophthalmic |
Pharmacokinetic data | |
Bioavailability | Absorbed systemically, but below detectable levels (less than 10 ng/mL) |
Protein binding | ~60% |
Half-life | 111 days |
Excretion | Renal (60%) |
Identifiers | |
CAS number | 138890-62-7 |
ATC code | S01EC04 |
PubChem | CID 68844 |
DrugBank | DB01194 |
ChemSpider | 62077 |
UNII | 9451Z89515 |
KEGG | D00652 |
ChEBI | CHEBI:3176 |
ChEMBL | CHEMBL220491 |
Chemical data | |
Formula | C12H21N3O5S3 |
Mol. mass | 383.51 g/mol |
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