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1-O-Acetyl-2,3,5-Tri-O-Benzoyl-β-D-Ribofuranose Acetyltribenzoylribose 1-acetyl-2,3,5-tribenzoyl-β-D-ribofuranose
1-O-Acetyl-2,3,5-Tri-O-Benzoyl-β-D-Ribofuranose
Molecular Formula: C28H24O9
Molecular weight: 504.48
CAS No.: 6974-32-9
EC No.: 230-220-4
Item |
Specification |
---|---|
Appearance |
White to off-white crystalline solid |
Assay (HPLC), % |
≥98 |
Specific Rotation [α]20/D, ° |
+43±1(c=1.0,CH2Cl2) |
Melt point, ℃ |
128-131 |
Ash, % |
≤1.0 |
Water, % |
≤1.0 |
TLC |
Single spot |
Characteristics: The product is white or off-white crystalline solid. It is soluble in alcohol but insoluble in water.
Uses: The product is an important pharmaceutical material and intermediate. It is used in synthesis anti-tumor drugs such as Azacitidine and Selenazofurin, nucleoside antibiotics Toyocamycin, and 2-chloro-N6-methyl adenosine use as vasodilators or hypotensive and/or anticoagulant drugs, etc. It is also use in synthesis the following compounds ¢Ù The analogues of adenosine, uridine, guanosine, cytidine, purine nucleosides that possess antitumor activity, for example, thiazolo[4,5-d]/ pyrazolo[3,4 d]/ pyrido[2,3-d]/ pyrrolo[2,3-d] / or imidazo[4,5-d]pyrimidone nucleoside, thiazolecarboxamide nucleoside, phosphazole[4,5-d]pyrimidines nucleoside, halo-imidazo[4,5-c]pyridine (or imidazo[4,5-c]pyridin-4-one) nucleoside, 2- or 7-chloro(fluoro) -9-deazanosine, Clitocine and 2-fluoro- / or 7-methyl-9-deazanosine which having anti-leukemia. ¢ÚVarious antiviral and antibacterial activity compounds, for example, 5-butylpyrimidine nucleosides having anti- polio and IHD strain vaccinia virus, benzylthio purine nucleoside having anti-toxoplasma gondii virus, N3,5'-Cyclo-4-(β-D-ribosyl)-vic-triazolo[4,5-b]pyridin-5-one and its analogs having anti- flavivirus especially hepatitis C virus, thieno[2,3-d] pyrimidine nucleoside having anti-E. coli activity, isatin ribonucleosides having anti-herpes simplex virus(HSV), N-ribosyl 2- and 8-halo-4H-1,4-benzothiazine having both anti-B. subtilis and anthelmintic activity, phenothiazines nucleoside having both anti-C. albicans, coagulase negative staphylococci strain and antioxidant, 3- uoro-10H-phenothiazines nucleosides having both anti- P. aeruginosa, E. coli, S. aureus, B. cereus and antioxidant, thieno[2,3-d]pyrimidine-thio-ribonucleosides having anti- E. coli, B. subtilis, C. albicans and A. niger, pyrido[2,3-d]pyridimines nucleosides having anti- E. coli, S. aureus, A. niger and A. flavus, ribosyl-1,2,4-triazin-6(1H)-/ones or thiones having anti- A. fumigatus, Penicillium, Syncephalastrum racemosum, C. albicans and E. coli, 6-benzylamino-2-thio-pyrimidinone nucleoside having anti-E. coli, S. aureus, C. albicans. ¢Û Deaminase inhibitor triazolo[3,4f] triazine-C-nucleoside, Toll-like receptor agonist pyrido[2,3-d] pyrimidone nucleoside, queuosine (a kind of T-RNA nucleoside), pterin ribonucleosides, deoxyriboses and its derivatives.
Storage: Maintain in cool, dry containment.
Package: 10kg/drum or as customer require.
Expiration Date: 1 years.
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Founded in 2008, East Chemsources Limited is a professional manufacturer of supplier in food and pharmaceutical field in China.
Through more than four years development, QINGDAO EAST CHEMSOURCES TRADE CO.,LTD,there is new branch office Qingdao East Chemsources Limited,our company has developed from single product at first to providing solution to finished products now, is committed to providing solutions for success and growth through long term relationships.
Currently, our products have been exported to more than 50 countries all over the world. Our service is accomplished by providing good quality solution that matches the specifications of our clients at competitive price. Our products will derive from trusted sources and arrive to our clients in time and well arranged manner, be creating the greatest benefits for our customers.
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