Metronidazole CAS: 443-48-1

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Metronidazole 2-Methyl-5-nitroimidazole-1-ethanol 443-48-1

Chemical name: 2-Methyl-5-nitro-1-imidazoleethanol; (2-Methyl-5-nitro-1-imidazolee; 2-(2-methyl-5-nitroimidazol-1-yl)ethanol; fossyol

CAS No. :443-48-1

Molecular Formula:C6H9N3O3

Molecular Weight:171.15

EINECS:207-136-1

Category: Disinfectant and antiseptic

Item		Specification	Result
Appearance		A white or yellowish crystalline powder	Comply
SOLUBILITY		SLIGHTLY SOLUBLE IN WATER,IN ACETONE,IN ALCOHOL AND IN METHYLENE CHLOROFORM,VERY SLIGHTLY SOLUBLE IN ETHER	COMPLY
IDENTIFICATION A),B)		a) MELTING POINT 159-163°C	A) 160.1-160.5°C
IDENTIFICATION A),B)		b) SPECIFIC ABSORBANCE 365-389	B) 377
LOSS ON DRYING		0.5% MAX	0.15%
SULPHATE ASHES		0.1% MAX	0.07%
HEAVY METAL		20PPM MAX	LESS THAN 20PPM
RESIDUAL SOLVENTS		ETHANEDIOL LESS THAN 620PPM	LESS THAN 620PPM
PARTICLE SIZE		40-60MESH	COMPLY
APPEARANCE OF SOLUTION		SUSPENSION 2	COMPLY
APPEARANCE OF SOLUTION		AND SOLUTION GY6	COMPLY
RELATED SUBSTANCE	1) IMPURITY	0.1%MAX	0.06%
	2)TOTAL IMPURITY	0.2%MAX	0.14%
	3)DISREGARD LIMITED	0.01% MAX	PASS
ASSAY		99.0%-101.0%

Item		Specification	Result
Appearance		A white or yellowish crystalline powder	Comply
SOLUBILITY		SLIGHTLY SOLUBLE IN WATER,IN ACETONE,IN ALCOHOL AND IN METHYLENE CHLOROFORM,VERY SLIGHTLY SOLUBLE IN ETHER	COMPLY
IDENTIFICATION A),B)		a) MELTING POINT 159-163°C	A) 160.1-160.5°C
IDENTIFICATION A),B)		b) SPECIFIC ABSORBANCE 365-389	B) 377
LOSS ON DRYING		0.5% MAX	0.15%
SULPHATE ASHES		0.1% MAX	0.07%
HEAVY METAL		20PPM MAX	LESS THAN 20PPM
RESIDUAL SOLVENTS		ETHANEDIOL LESS THAN 620PPM	LESS THAN 620PPM
PARTICLE SIZE		40-60MESH	COMPLY
APPEARANCE OF SOLUTION		SUSPENSION 2	COMPLY
APPEARANCE OF SOLUTION		AND SOLUTION GY6	COMPLY
RELATED SUBSTANCE	1) IMPURITY	0.1%MAX	0.06%
	2)TOTAL IMPURITY	0.2%MAX	0.14%
	3)DISREGARD LIMITED	0.01% MAX	PASS
ASSAY		99.0%-101.0%