Sunifiram / Dm-235 ...

Sunifiram / Dm-235 powder CAS:314728-85-3

Sunifiram / Dm-235 powder CAS:314728-85-3

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Sunifiram Dm-235 314728-85-3

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  • Appearance:white powder
  • Application:nootropic medicine
  • PackAge:foil bag
  • ProductionCapacity:|Metric Ton|Day
  • Storage:cool and dry place
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Sunifiram / Dm-235 powder CAS:314728-85-3 

Name: Sunifiram

other name: Dm-235
Synonyms:1-(4-Benzoyl-1-piperazinyl)-1-propanone;1-Benzoyl-4-(1-oxopropyl)-piperazine;
1-(4-Benzoylpiperazin-1-yl)propan-1-one;1-Benzoyl-4-propanoylpiperazine
CAS:314728-85-3
MF:C14H18N2O2
MW:246.30492
Sunifiram (DM-235) is a synthetic derivative of Piracetam, although due to breaking the pyrrolidone backbone it is no longer in the Racetam class of drugs (yet by being derived from them, it is still commonly associated with this class).
Packing:As required
 
2. Sunifiram Application: 
 
Sunifiram has mechanisms similar to Nefiracetam in the hippocampus, and similar to that drug sunifiram shows anti-amnesiac properties and is potentially a cognitive enhancer. Its anti-amnesiac activity is several orders of magnitude greater than piracetam on a per weight basis, and preliminary evidence suggest it has a similarly low toxicity profile.
 
This compound is known as an AMPAkine due to exerting most of its actions via the AMPA receptor (one of the three main subsets of glutamate receptors, alongside NDMA and kainate). This enhancement of AMPA function seems to also rely on enhancing signalling via the Glycine binding site of NMDA receptors, although one minimal signalling goes through the NMDA receptor then the benefits on AMPA receptors seem dose-dependent.
 
3. POTENTIAL BENEFITS OF SUNIFIRAM
 
According to clinical research on animal test subjects, it has been determined that Sunifiram has a host of potential benefits.  Some of these potential benefits include:
 
1) Improved decision making
2) A greater ability to convert short-term memory into long-term memory
3) Improved motor skills via increased control over muscle contraction
4) Enhanced memory and retention of learned information and activities
 
4. Mechanisms of Actions
 
Sunifiram operates by activating AMPA receptors; that is, the receptors that are responsible for the mediation of synaptic transmission in the central nervous system.  Its mechanics also increases phosphorylation of AMPAR and NMDAR through protein kinase activation, which in turn enhances long-term potentiation - that is, an enhancement in signal transmission between two neurons resulting from simultaneous stimulation.
 
The kinase activation that is influenced by Sunifiram also improves cognitive defects.  Additionally, Sunifiram works in the cerebral cortex of animal test subjects by assisting in the release of acetylcholine, the organic molecule that acts as a neurotransmitter in a host of various organisms.  These operational mechanisms enable Sunifiram to exert anti-amnesiac properties.
 
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