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Details:
Coluracetam powder / CAS No.:135463-81-9
Name:Coluracetam
Molecular Formula:C19H23N3O3
CAS No.:135463-81-9
Purity:99%
Synonyms:N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide
Molecular Weight:341.40
Appearance:white crystal powder
Boiling Point:634.1°C at 760 mmHg °C
Port:SH
Application:mainly applied to promote intellectual product. /raw material used in Synthesis/ pharmaceutical raw material
Coluracetam (BCI-540) is a nootropic drug of the racetam family.Coluracetam (formerly known as MKC-231) was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California.Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD).BrainCells Inc is currently out-licensing the drug for this purpose.It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.
Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system
Hubei God bull Pharmaceutical Co.,Ltd is established in 2010 , a leading pharmaceutical intermediate factory and special in steroid powder,injection,tablet ,SARMS,HGH, Peptide.According to the GMP standard,the company has built 10000 m2 plant equipped the advanced equipment. The factory has a complete Q.A. & Q.C.system.We own several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and UV spectrophotometer to analyze and control the products. The company has gotten the approval of ISO9001.We have the authority of export and import, the fine chemical, biochemical, pharmaceutical & its intermediates distributed by the company are sold both in the domestic and international market and highly recommended by our clients