522-17-8(DEGUELIN)

522-17-8(DEGUELIN)

522-17-8(DEGUELIN)

Min.Order / FOB Price:Get Latest Price

1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 97%-99.9%
  • Payment Terms : T/T,Other

Keywords

522-17-8 DEGUELIN C23H22O6

Quick Details

  • Appearance:white powder
  • Application:An important raw material
  • PackAge:as customer's request
  • ProductionCapacity:500|Metric Ton|Week
  • Storage:According to the requirements
  • Transportation:by sea/air

Superiority:


				

					 

				

					 

				

					 

				

					Coreychem

				

					Henan CoreyChem Co., Ltd, facing global High-tech pharmaceutical raw materials, high value-added new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade.

				

					 

				

					 

				

					Innovative

				

					Henan Coreychem is committed to continuously explore new compound synthesis technology in recent years,we were on enzyme catalysis, catalytic metal complexes in the total synthesis was tested and achieved good results: S.lycopersicum (+) - Aszonalenin (+) - Citrinadin B Total Synthesis of ( − )-Brevicompanine B by Ir-Catalyzed Total Synthesis of (+)-Citrinadin B

				

					 

				

					 

				

					servers

				

					 

				

					Intermediates

				

					 

				

					Electronic chemicals

				

					 

				

					Catalyst

				

					Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.

					
		

	




	base.



	

		
			

				
					

						
							

								
									
								
									

										
											

												
													Coreychem
											

											

												
													Henan CoreyChem Co., Ltd, facing global High-tech pharmaceutical raw materials, high value-added new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade.
											

											

												
													
											

										
									

										
							

						
					

						
				
					 
				
					

						
							

								
									 
							

							

								
									Innovative
							

							

								
									Henan Coreychem is committed to continuously explore new compound synthesis technology in recent years,we were on enzyme catalysis, catalytic metal complexes in the total synthesis was tested and achieved good results: S.lycopersicum (+) - Aszonalenin (+) - Citrinadin B Total Synthesis of ( − )-Brevicompanine B by Ir-Catalyzed Total Synthesis of (+)-Citrinadin B
							

							

								
									
							

						
					

						
			

		
	





	
		

			
				 
		

		

			
				
			
		

	




	

		
			

				
					

						
							

								
									
								
									

										
											

												
													Coreychem
											

											

												
													Henan CoreyChem Co., Ltd, facing global High-tech pharmaceutical raw materials, high value-added new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade.
											

											

												
													
											

										
									

										
							

						
					

						
				
					 
				
					

						
							

								
									 
							

							

								
									Innovative
							

							

								
									Henan Coreychem is committed to continuously explore new compound synthesis technology in recent years,we were on enzyme catalysis, catalytic metal complexes in the total synthesis was tested and achieved good results: S.lycopersicum (+) - Aszonalenin (+) - Citrinadin B Total Synthesis of ( − )-Brevicompanine B by Ir-Catalyzed Total Synthesis of (+)-Citrinadin B
							

							

								
									
							

						
					

						
			

		
	





	
		

			
				 
		

		

			
				
			
		

	




	 



                        

                                            

                            
Details:

                            

	

		

			

				

					

						

							

								

									

										

											

												

													

														

															

																

																	

																		

																			

																				

																					

																						

																							

																								

																									

																										

																											

																												

																													

																														

																															

																																

																																	

																																		

																																			

																																				

																																					

																																						

																																							

																																								

																																									
																																										

																																											
																																												DEGUELIN Basic information
																																										

																																									
																																								

																																								

																																									
																																										

																																											
																																												Product Name:
																																											
																																												DEGUELIN
																																										

																																										

																																											
																																												Synonyms:
																																											
																																												(7as-cis)-oxy-;3h-bis(1)benzopyrano(3,4-b:6’,5’-e)pyran-7(7ah)-one,13,13a-dihydro-9,10-dimeth;(-)-DEGUELIN;DEGUELIN;(7AS,13AS)-13,13A-DIHYDRO-9,10-DIMETHOXY-3,3-DIMETHYL-3H-BIS[1]BENZOPYRANO[3,4-B:6',5'-E]PYRAN-7(7AH)-ONE;(7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-(3H)-bis[1]benzopyrano[3.4-b.6'.5'-e]pyran-7(7aH)-one;12a-DEOXYTEPHROSIN;(7aS)-3,3-Dimethyl-9,10-dimethoxy-7,7aα,13,13aα-tetrahydro-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7-one
																																										

																																										

																																											
																																												CAS:
																																											
																																												522-17-8
																																										

																																										

																																											
																																												MF:
																																											
																																												C23H22O6
																																										

																																										

																																											
																																												MW:
																																											
																																												394.42
																																										

																																										

																																											
																																												EINECS:
																																											
																																												 
																																										

																																										

																																											
																																												Product Categories:
																																											
																																												Miscellaneous Natural Products;Antitumour
																																										

																																										

																																											
																																												Mol File:
																																											
																																												522-17-8.mol
																																										

																																										

																																											
																																												DEGUELIN Structure
																																										

																																									
																																								

																																							

																																							

																																								

																																									
																																										

																																											
																																												 
																																										

																																										

																																											
																																												DEGUELIN Chemical Properties
																																										

																																									
																																								

																																								

																																									
																																										

																																											
																																												Melting point 
																																											
																																												85-87 °C(lit.)
																																										

																																										

																																											
																																												alpha 
																																											
																																												D27 -97.2° (c = 0.2 in benzene)
																																										

																																										

																																											
																																												storage temp. 
																																											
																																												−20°C
																																										

																																										

																																											
																																												solubility 
																																											
																																												DMSO: >10 mg/mL
																																										

																																										

																																											
																																												form 
																																											
																																												solid
																																										

																																										

																																											
																																												color 
																																											
																																												white to yellow
																																										

																																										

																																											
																																												optical activity
																																											
																																												[α]/D -70 to -80°, c = 0.2 in methanol
																																										

																																									
																																								

																																							

																																							

																																								

																																									
																																										

																																											
																																												 
																																										

																																										

																																											
																																												Safety Information
																																										

																																									
																																								

																																								

																																									
																																										

																																											
																																												Safety Statements 
																																											
																																												22-24/25
																																										

																																										

																																											
																																												WGK Germany 
																																											
																																												3
																																										

																																										

																																											
																																												RTECS 
																																											
																																												DX1500000
																																										

																																										

																																											
																																												HS Code 
																																											
																																												29329990
																																										

																																									
																																								

																																							

																																							

																																								

																																									
																																										

																																											
																																												
																																										

																																										

																																											
																																												MSDS Information
																																										

																																									
																																								

																																								

																																									

																																										
																																											

																																												
																																													Provider
																																												
																																													Language
																																											

																																											

																																												
																																													SigmaAldrich
																																												
																																													English
																																											

																																										
																																									

																																								

																																							

																																							

																																								

																																									
																																										

																																											
																																												 
																																										

																																										

																																											
																																												DEGUELIN Usage And Synthesis
																																										

																																									
																																								

																																								

																																									
																																										

																																											
																																												Uses
																																											
																																												antineoplastic, antiviral, insecticide, ornithine decarboxylate inhibitor
																																										

																																										

																																											
																																												Uses
																																											
																																												Deguelin exhibits potent apoptotic and antiangiogenic activities in a variety of transformed cells and cancer cells. Deguelin also exhibits potent tumor suppressive effects in xenograft tumor models for many human cancers.
																																										

																																										

																																											
																																												Biological Activity
																																											
																																												Anticancer and antiviral agent; chemopreventive and pro-apoptotic. Inhibits phorbol ester-induced ornithine decarboxylase and NADH:ubiquinone oxidoreductase activities (IC 50 values are 11 and 6.9 nM respectively). Inhibits PI 3-kinase and reduces pAkt levels in pre-malignant and malignant human bronchial epithelial cells. Active in vivo .
																																										

																																									
																																								

																																							

																																						

																																					

																																				

																																			

																																		

																																	

																																

																															

																														

																													

																												

																											

																										

																									

																								

																							

																						

																					

																				

																			

																		

																	

																

															

														

													

												

											

										

									

								

							

						

					

				

			

		

	





	 



                        

                

                

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