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Benazepril hydrochloride Benazepril HCL 86541-74-4
CAS Number:86541-74-4
Name:1H-1-Benzazepine-1-aceticacid,3-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-,hydrochloride (1:1), (3S)-
Superlist Name:Benazepril hydrochloride
Formula:C24H29ClN2O5
Molecular Weight:460.96
Synonyms:1H-1-Benzazepine-1-aceticacid,3-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-,monohydrochloride, (3S)- (9CI);1H-1-Benzazepine-1-acetic acid,3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-,monohydrochloride, [S-(R*,R*)]-;CGS 14824A;CGS14824A HCl;Lotensin;Lotension;
Melting Point:188-190 °C
Boiling Point:691.2 °C at 760 mmHg
Flash Point:371.8 °C
Solubility:DMSO: ~34 mg/mL, soluble
Test Item |
Analysis Specification |
Result |
||
Description |
A white or almost white crystalline power |
Conforms |
||
Appearance of solution |
Clear and colourless |
Conforms |
||
Identification |
A,B,C |
Positives |
||
Optical rotation |
-0.1°~ +0.1° |
0° |
||
Melting point |
114~117°C |
114.5~115.6°C |
||
Heavy metals |
NMT 10ppm |
<10ppm |
||
Impurity A |
NMT0.5% |
0.06% |
||
Individual impurity |
NMT0.2% |
0.12% |
||
Total impurity |
NMT1.0% |
0.30% |
||
Loss on drying |
NMT0.5% |
0.28% |
||
Sulphated ash |
NMT0.1% |
0.03% |
||
Assay |
99.0%~100.5% |
99.9% |
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