Bentonite compet...

Bentonite    competitive product
Bentonite    competitive product

Bentonite competitive product

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1 Kilogram

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  • Purity: 99%
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  • Application:pharmaceutical raw materials
  • PackAge:foil aluminium bag/vacuum packing
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Product Name: Bentonite
Synonyms: bentonite,sodiummontmorillonite;bentonite2073;Bentonite812,organic;bentonitepowder;colloidalclay;hi-jel;imvitei.g.b.a;magbond
CAS: 1302-78-9
MF: Al2O3.4(SiO2).H2O
MW: 360.31
EINECS: 215-108-5
Product Categories: -;UVCBs-inorganic
Mol File: Mol File
Bentonite Structure
 
Bentonite Chemical Properties
density  2~3g/cm3
solubility  Practically insoluble in water and in aqueous solutions. It swells with a little water forming a malleable mass.
form  powder
Water Solubility  Insoluble in water and forms a colloidal solution.
Merck  14,1055
Stability: Stable.
CAS DataBase Reference 1302-78-9
 
Safety Information
Risk Statements  20/22-8
Safety Statements  22-24/25
WGK Germany  3
RTECS  CT9450000
TSCA  Yes
Hazardous Substances Data 1302-78-9(Hazardous Substances Data)
MSDS Information
Provider Language
Bentonite English
SigmaAldrich English
ALFA English
 
Bentonite Usage And Synthesis
Chemical Properties gel, or solid if dry
Chemical Properties Bentonite is a light yellow, creamy, pale brown or gray to black powder or granules.
Chemical Properties Bentonite is a crystalline, claylike mineral, and is available as an odorless, pale buff, or cream to grayish-colored fine powder, which is free from grit. It consists of particles about 50–150 mm in size along with numerous particles about 1–2μm. Microscopic examination of samples stained with alcoholic methylene blue solution reveals strongly stained blue particles. Bentonite may have a slight earthy taste.
Uses Bentonite is a general purpose additive that is used as a pigment and colorant and to clarify and stabilize wine.
Uses filler in cosmetics and other products, gel, or solid if dry
Uses As of Fuller's earth; as emulsifier for oils; as a base for plasters. Pharmaceutic aid (suspending agent).
Uses bentonite (bentonite clay) is used to regulate the viscosity and suspension properties of a cosmetic formulation. It also acts as an overall formula stabilizer. Bentonite’s water-absorption capabilities allow it to form a gelatinous mass. Considered a noncomedogenic raw material, bentonite is a colloidal aluminum silicate clay.
Production Methods Bentonite is a native, colloidal, hydrated aluminum silicate, found in regions of Canada and the USA. The mined ore is processed to remove grit and nonswelling materials so that it is suitable for pharmaceutical applications.
Definition A type of clay that is used as an adsorbent in making paper. The gelatinous suspension it forms with water is used to bind together the sand for making iron castings. Chemically bentonite is an aluminosilicate of variable composition.
Pharmaceutical Applications Bentonite is a naturally occurring hydrated aluminum silicate used primarily in the formulation of suspensions, gels, and sols, for topical pharmaceutical applications. It is also used to suspend powders in aqueous preparations and to prepare cream bases containing oil-in-water emulsifying agents.
Bentonite may also be used in oral pharmaceutical preparations, cosmetics, and food products. In oral preparations, bentonite, and other similar silicate clays, can be used to adsorb cationic drugs and so retard their release. Adsorbents are also used to mask the taste of certain drugs. 
Bentonite has been investigated as a diagnostic agent for magnetic resonance imaging.
Therapeutically, bentonite has been investigated as an adsorbent for lithium poisoning.
Agricultural Uses Bentonite, also known as montmorillonite, volcanic clay, soap clay and amargosite, is a soft, plastic, lightcolored, porous rock consisting largely of colloidal silica. Composed essentially of clay minerals, it swells extensively when wet. Bentonite belongs chiefly to the montmorillonite group and has two varieties: (a) sodium bentonite, with a high swelling capacity in water, and (b) calcium bentonite, with negligible swelling capacity.
Bentonite is used variously as a suspending aid, a gelatinous slurry to extinguish fire, a paint thickener, and as a sealant for earthen pots. Bentonite is also widely used in metallurgy, soap manufacture, and in petroleum refining because of its high decolorizing power and strong adsorbing capacity.
Agricultural Uses Clays exist in many forms, of which montmorillonite is one form. Kaolinite and montmorillonite, which are clay minerals, have different layer structures with differing abilities to absorb and retain water, and to adsorb and exchange cations.
Montmorillonites have an expanding structure (2: 1) and have high cation exchange capacity (80 to 120 mg per 100 g). They have abundant black clay soils. Other minerals in this group are biedellite and nontronite.
Safety Profile Poison by intravenous route causing blood clotting. Questionable carcinogen with experimental tumorigenic data.
Safety Bentonite is mainly used in topical pharmaceutical formulations but has also been used in oral pharmaceutical preparations, food products, and cosmetics.
Following oral administration, bentonite is not absorbed from the gastrointestinal tract. Bentonite is generally regarded as a nontoxic and nonirritant material.
LD50 (rat, IV): 0.035 g/kg
Potential Exposure This material is used as Fuller’s earth; as a mineral, natural, or synthetic fiber; as an emulsifier for oils; as a base for plasters; in cosmetics, in polishes and abrasives; as a food additive and others. Bentonites are aluminate silicate and can contain crystalline silica. The content varies widely from less than 1% to about 24% .
storage Bentonite is hygroscopic, and sorption of atmospheric water should be avoided.
Aqueous bentonite suspensions may be sterilized by autoclaving. The solid material may be sterilized by maintaining it at 1708℃ for 1 hour after drying at 1008℃.
Bentonite should be stored in an airtight container in a cool, dry place.
Shipping Bentonite is not cited in the DOT Performance- Oriented Packaging Standards.
Incompatibilities Substance is a weak acid in water; avoid contact with strong alkaline material. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Incompatibilities Aqueous bentonite suspensions retain their viscosity above pH 6, but are precipitated by acids. Acid-washed bentonite does not have suspending properties. The addition of alkaline materials, such as magnesium oxide, increases gel formation.
Addition of significant amounts of alcohol to aqueous preparations will precipitate bentonite, primarily by dehydration of the lattice structure.
Bentonite particles are negatively charged and flocculation occurs when electrolytes or positively charged suspensions are added. Bentonite is thus said to be incompatible with strong electrolytes, although this effect is sometimes used beneficially to clarify turbid liquids.
The antimicrobial efficacy of cationic preservatives may be reduced in aqueous bentonite suspensions, but nonionic and anionic preservatives are unaffected.
Bentonite is incompatible with acriflavine hydrochloride.
Waste Disposal Land fill disposal.
Regulatory Status Accepted in Europe as a food additive in certain applications. Included in the FDA Inactive Ingredients Database (oral capsules, tablets and suspensions, topical suspensions, controlled release transdermal films and vaginal suppositories). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

 

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