Baclofen 1134-47-0 Baclofen99%
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Name: Baclofen
Molecular Formula: C10H12ClNO2
Molecular Weight: 213.66
CAS No: 1134-47-0
Purity:99%min
Appearance: White or almost white powder
Specification:
Items | Specifications | Results |
Appearance | white crystalline hygroscopic powder | Conform |
Identification | IR in accordance with USP RS | Conform |
Specific optical Rotation [α] | -29.0°∼-32° | -31.4° |
pH | 5.5-9.5 | 7.2 |
Moisture content | ≤4% | 0.25% |
Residue on ignition | ≤0.5% | 0.03% |
Chloride | ≤0.4% | <0.4% |
Heavy metals | <0.01% | <0.001 |
Limit of potassium | ≤0.2% | 0.00% |
Limit of Sodium | ≤0.1% | 0.01% |
Assay | 97.0% ∼103.0% | 99.40% |
Residue solvents(ethanol) | ≤0.5% | 0.07% |
Cyanide | Not be detected | N.D. |
Conclusion | The results complies with USP36. |
Function:
Baclofen powder can be used as Specific GABA-B receptor agonist. Muscle relaxant (skeletal). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. In addition, research has shown baclofen to be effective in the treatment of alcohol dependence and withdrawal, by inhibiting both withdrawal symptoms and cravings.
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