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Product Name: | 5-(2-Hydroxyethyl)-4-methylthiazole |
Synonyms: | A875 Cell;4-Methyl-5-thiazoleethanol, 98% 100ML;5-(2-HYDROXYETHYL)-4-METHYLTHIAZOLE FOR;Methyl-5-thiazoleetha;4- Methyl-5- thiazolealcohol;Methyl-5-hydroxyethyl thiazole;5-(2-Hydroxyethyl)-4-methylthiazole in stock Factory;4-Methyl-5-Hydroxyethyl Thiazole (Meaty, Beany & Milky) |
CAS: | 137-00-8 |
MF: | C6H9NOS |
MW: | 143.21 |
EINECS: | 205-272-6 |
Product Categories: | -;alcohol;Thiazole;Alkohols;thiazole Flavor |
Mol File: | 137-00-8.mol |
|
5-(2-Hydroxyethyl)-4-methylthiazole Chemical Properties |
Boiling point | 135 °C7 mm Hg(lit.) |
density | 1.196 g/mL at 25 °C(lit.) |
refractive index |
n |
FEMA | 3204 | 4-METHYL-5-THIAZOLEETHANOL |
Fp | >230 °F |
storage temp. | Store below +30°C. |
solubility | alcohol: soluble(lit.) |
form | liquid (clear, viscous) |
color | deep yellow |
Specific Gravity | 1.196 |
Odor | meaty, roasted odor |
Sensitive | Stench |
Merck | 14,6126 |
JECFA Number | 1031 |
BRN | 114249 |
InChIKey | BKAWJIRCKVUVED-UHFFFAOYSA-N |
CAS DataBase Reference | 137-00-8(CAS DataBase Reference) |
NIST Chemistry Reference | 5-Thiazoleethanol, 4-methyl-(137-00-8) |
EPA Substance Registry System | 5-Thiazoleethanol, 4-methyl-(137-00-8) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-24/25-7/9 |
RIDADR | UN 3334 |
WGK Germany | 3 |
F | 13 |
Hazard Note | Irritant/Stench |
TSCA | Yes |
HS Code | 29341000 |
MSDS Information |
Provider | Language |
---|---|
5-(2-Hydroxyethyl)-4-methylthiazole | English |
SigmaAldrich | English |
ACROS | English |
ALFA | English |
5-(2-Hydroxyethyl)-4-methylthiazole Usage And Synthesis |
Content analysis | It was determined by gas chromatography (GT-10-4) using a nonpolar column method. |
Toxicity | GRAS (FEMA) |
Usage limit FEMA | soft drinks, cold drinks, candy, baked goods, jelly, pudding, jelly sugar, seasonings, meat products, meat soup, milk and dairy products as well as cereal product: 55.0mg/kg. |
Chemical properties | It appears as colorless to pale yellow viscous oily liquid. The color will turn dark after being subject to long-term storage. It emit unpleasant thiophene compound odor with high dilution generating nut aroma. The boiling point is 103 ° C (133 Pa), or 135 ° C (933 Pa). It is easily soluble in water, soluble in ethanol, ether, benzene and chloroform. |
Application |
|
Preparation | It is obtained from the reduction of 4-methyl thiazole 5-ethyl acetate reduction with lithium aluminum hydride. |
Description | 4-Methy 1-5-thiazoleethanol has the characteristic disagreeable odor of thiazole compounds. It is somewhat pleasant and nut-like on extreme dilution. It may be prepared by reduction of ethyl- 4-methylthiazole-5-acetate using LiAlH4; by condensation of thioformamide with bromoacetopropanol or with y,y-dichloro-y,ydiacetodipropyl ether. |
Chemical Properties | 4-Methyl-5-thiazoleethanol has a disagreeable odor typical of thiazole compounds; somewhat pleasant, reminiscent of beef and nut-like, on extreme dilution |
Chemical Properties | Colorless to light yellow liqui |
Occurrence | Reported found in grilled and roasted beef, cognac, brandy, Finnish whiskey, cocoa, peanuts, beans and malt. |
Preparation | By reduction of ethyl-4-methylthiazole-5-acetate using LiAlH4; by condensation of thioformamide with bromoacetopropanol or with γ, y-dichloro-γ,γ-diacetodipropyl ether |
Definition | ChEBI: A 1,3-thiazole that is thiazole substituted by a methyl group at position 4 and a 2-hydroxyethyl group at position 5. |
Taste threshold values | Taste characteristics at 20 ppm: meaty, brothy, roasted, metallic and nutty. |
5-(2-Hydroxyethyl)-4-methylthiazole Preparation Products And Raw materials |
Preparation Products | 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide |
Raw materials | Lithium aluminium hydride-->THIOFORMAMIDE-->4-Methylthiazole |
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