CasNo.2257-09-2,Phenylethyl isothiocyanate competitive product,(2257-09-2) Suppliers

1 Kilogram	FOB Price: USD 0.1000

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : T/T,Other

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Quick Details

Appearance:according to email quotation
Application:pharmaceutical raw materials
PackAge:foil aluminium bag/vacuum packing
ProductionCapacity:100|Kilogram|Week
Storage:Keep in dry and cool condition
Transportation:by air or by sea

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Coreychem competetive product

High quality and favourable price

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Advanced and completed testing facilities

High Cost-Effective and stable supplying

Coreychem focus on high complex new type intermediates and fine chemical custom synthesis,scale-up production and rare chemicals trade.Product category including Intermediates&API,Catalyst and Electronic Chemicals.Covering 811 square meters R&D center,with 45 person R&D team,our synthesis level is well-known to the industry,which are exported to France,Poland,Czech,Ukraine,Spain,Switzerland,etc...

Details:

Product Name:	Phenylethyl isothiocyanate
Synonyms:	2-Phenylethyl isothiocyanate, Phenethyl isothiocyanate;β-Phenylethyl isothiocyanate, Phenethyl isothiocyanate;Isothiocyanic acid phenethyl;Phenylethyl isothiocyanate,96%;PHENETHYL GLUCOSINOLATE POTASSIUM SALT(GLUCONASTURTIIN)(RG);Isothiocyanic Acid 2-Phenylethyl Ester Phenethyl Isothiocyanate;PHENYLETHYL ISOTHIOCYANATE(P)(REQUEST QUOTE);Phenethyl isothiocyanate 99%
CAS:	2257-09-2
MF:	C9H9NS
MW:	163.24
EINECS:	218-855-5
Product Categories:	Aromatics Compounds;Aromatics;Sulfur & Selenium Compounds
Mol File:	2257-09-2.mol

Phenylethyl isothiocyanate Chemical Properties

Melting point	143～145℃
Boiling point	75 °C0.25 mm Hg
density	1.094 g/mL at 25 °C(lit.)
refractive index	n20/D 1.5888(lit.)
FEMA	4014 \| PHENETHYL ISOTHIOCYANATE
Fp	>230 °F
storage temp.	Refrigerator, Under Inert Atmosphere
form	Liquid
Specific Gravity	1.09
color	Clear colorless to yellow
Water Solubility	insoluble
Sensitive	Moisture Sensitive
Merck	14,7226
JECFA Number	1563
BRN	2084162
InChIKey	IZJDOKYDEWTZSO-UHFFFAOYSA-N
CAS DataBase Reference	2257-09-2(CAS DataBase Reference)
NIST Chemistry Reference	Benzene, (2-isothiocyanatoethyl)-(2257-09-2)
EPA Substance Registry System	Benzene, (2-isothiocyanatoethyl)-(2257-09-2)

Safety Information

Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38-42-42/43
Safety Statements	23-26-36-36/37
RIDADR	UN 2206 6.1/PG 3
WGK Germany	3
RTECS	NX9115000
F	10-23
TSCA	Yes
HazardClass	8
PackingGroup	III
HS Code	29309090
Toxicity	LD50 in mice (mg/kg): 700 orally; 150 s.c.; 50 i.v. (Lichtenstein)

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

Phenylethyl isothiocyanate Usage And Synthesis

Chemical Properties	Light Yellow Liquid
Chemical Properties	Phenethyl isothiocyanate has a strong green irritating odor.
Uses	Flavor ingredient; provides the hot or burning sensation in horseradish.
Definition	ChEBI: An isothiocyanate having a phenethyl group attached to the nitrogen. It is a naturally occurring compound found in some cruciferous vegetables (e.g. watercress) and is known to possess anticancer properties.
Preparation	Prepared by hydrolysis of gluconasturtiin, an abundant natural product present in cruciferous vegetables.
Anticancer Research	PEITC is a naturally occurring isothiocyanate, found mostly in cruciferous vegetablesincluding cauliflower, watercress, cabbage, Brussels sprouts, garden cress, broccoli,and bok choy. It shows chemopreventive and anticancer activity againstmelanoma, breast cancer, myeloma, human liver hepatoma, non-small cell lung cancer,cervical cancer, prostate cancer, and osteogenic sarcoma. It induces apoptosis in some drug resistance cell lines. Its mechanism of action is much diversified in variouscancer cells. It induces apoptosis in highly metastatic human non-small cell lungcancer, L9981 cells via caspase-3 activation, and cell cycle arrest in G2/M phase bymodulation of cyclin B1 expression while targeting MAPK/AP-1 pathway. In cervicalcancer cells, it increases the death receptor (DR4, DR5) expression, cleaves caspase-3, induces caspase-8, truncates BID, and downregulates ERK1/2 and MEKphosphorylation while maintaining the expression of JNK and phospho-p38MAPK. In human prostate cancer (DU 145) cell line, PEITC induces apoptosis byactivating caspase cascade pathway (Wang et al. 2012; Cheung and Kong 2010).