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100 Gram |
Negotiable |
Lapatinib Ditosylate Monohydrate Lapatinib Ditosylate 388082-78-8
Name |
Lapatinib | |
Synonyms | N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine |
Molecular Formula | C29H26ClFN4O4S | |
Molecular Weight | 581.06 | |
CAS Registry Number | 231277-92-2 |
HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture.
With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exporting pharmaceuticals, veterinary drugs, feed additives, intermediates, fine chemicals, plants extracts, pesticides, food & nutrition additives.
Thinkchem is good at offering excellent outsourcing services to overseas customers as well as laboratory support.
Custom manufacture
Thinkchem is good at offering contract manufacture and custom synthesis under confidential agreement timely and effectively, and providing sales service from grams ,kilograms to multi-tons particularly for pharmaceuticals and their intermediates discovery and development. Thinkchem is equipped with modern lab apparatus including HPLC, GC. TLC AND NMR, motivated by a team of highly qualified personnel using these equipments.
Staff
Thinkchem is composed of chemical technicians, analytical chemists, organic chemists, and chemical engineers educated in leading universities in china. Our staff is supported by a group of consultants from academia with expertise in chemical synthesis and analytical chemistry.
5 |
DESCRIPTION |
White to pale yellow colour viscous oil mass |
6 |
SOLUBILITY |
Soluble in dimethyl sulphoxide, slightly soluble in methanol, very slightly soluble in water. |
7
|
IDENTIFICATION BY |
|
a) By IR |
Infrared absorption spectrum of test should be concordant with the same preparation of reference working standard. |
|
b) By TLC |
To comply |
|
8 |
WATER CONTENT |
NMT 0.5% w/w |
9 |
SPECIFIC OPTICAL ROTATION |
Between +108 and +115 measured at 365 nm. |
10 |
RELATED SUBSTANCES KNOWN IMPURITY At RRT 0.7 ANY UNKNOWN IMPURITY TOTAL IMPURITY
|
NMT 0.3% NMT 0.15%
NMT 1.5% |
11 |
ASSAY BY HPLC |
98.0 % w/w to 101.0% w/w (on Anhydrous Basis) |
12 |
RESIDUE ON IGNITION |
NMT 0.1 % w/w |
13 |
HEAVY METALS |
NMT 10 ppm |
14 |
RESIDUAL SOLVENT METHANOL DMAC N-HEXANE ETHYL ACETATE |
NMT 3000 ppm NMT 1090 ppm NMT 2% NMT 6%Laparinib[CAS:231277-92-2] |
1. Well-trained professional sales team dedicated to source, audit and export.
2. Well-trained R & D team equipped with new knowledge, new ideas and new insights to support product development and innovation.
3. Well-established partnership with major pharmaceutical and chemical companies in china.
4. Wide range of products and efficient regulatory documentation offered to customers.
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