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pharmaceutical Grade Loratadine 79794-75-5 Loratadine
Loratadine is a medication used to treat allergies. This includes allergic rhinitis(hay fever) and hives. . It is taken by mouth.Common side effects include sleepiness, dry mouth, and headache.Serious side effects are rare and include allergic reactions,seizures, and liver problems.Use during pregnancy appears to be safe but has not been well studied. It is not recommended in children less than two years old.It is in the second-generation antihistamine family of medication.
Loratadine is indicated for the symptomatic relief of allergy such as hay fever (allergic rhinitis), urticaria (hives), chronic idiopathic urticaria,and other skin allergies.For allergic rhinitis (hay fever), loratadine is effective for both nasal and eye symptoms: sneezing, runny nose, itchy or burning eyes.
Loratadine
Assay: 99% min
CAS:79794-75-5
Molecular formula:C22H23ClN2O2
Molecular weight: 382.89
Purity: 99%
Appearance: White crystalline powder
Loratidine; Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate; 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester.
Loratadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Test Item |
Standard: USP |
Character |
White or off-white crystalline powder |
Melting range |
132~137 |
Identification |
IR spectrum similar to that of RS |
HPLC retention time similar to that of RS |
|
Related substance |
Total impurities: NMT0.3% |
Single impurity: NMT0.1% |
|
Heavy metals |
NMT 10ppm |
Loss on drying |
NMT0.5% |
Residue on ignition |
NMT0.1% |
Assay |
98.5%-101.0% |
Loratadine is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.
Loratadine is also used to treat skin hives and itching in people with chronic skin reactions.
Pharmaceutical intermediates, use as allergy drug loratadine synthesis.
Packing and Storage
1kg with double plastic container inside/Aluminum foil bag ;
25kg with double plastic container inside/Fiber drum outside.Or as your request.
Shipped in 3 days after payment.
1.Stored in a cool and dry well-closed container and in ventilated area.
2.kept away from moisture and strong light or high temperature.
3.Two years under well storage situation and stored away from direct sun light.
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