CasNo.159351-69-6,Sirolimus / Rapamycin Derivative CAS 159351-69-6 Everolimus Powder,(159351-69-6) Suppliers

1 Gram	FOB Price:USD 150.0000 -200.0000

Min.Order :1 Gram
Purity: 99%
Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram,Other

Keywords

Everolimus 159351-69-6 Everolimus Powder

Quick Details

Appearance:White powder
Application:1. Adult patients with advanced renal cell carcinoma who have failed to receive either sunitinib or sorafenib. 2. Unresectable, locally advanced or metastatic, well-differentiated (moderately diff...
PackAge:Aluminum foil bag,fluorinated bottles,carboard drums or as your special request.
ProductionCapacity:10|Metric Ton|Month
Storage:Store in cool & dry place. Keep away from strong light Shelf Life2 years when properly stored.
Transportation:1) Door to Door Service by DHL/FEDEX/EMS/TNT for package under 45kgs 2) Port to Port Service by Air for package more than 45kgs 3) Port to Port Service by Sea for package more than 500kgs

Superiority:

1) Provide costomers with "one-stop"packaging service,from research,development,production,export and so on.
2) We have our own R&D and production base,equipped with advanced production equipment and precision testing the Unitef States Pharmacopoeia(USP),the Britis Pharmacopoeia(EP) and other international advanced standards.All products are through the KOSGER,HALAL certification,the ISO quality management system certification and the HACCP certification.
3) More than 12 years of export experience.
4)Competitive price in China market.

Details:

Product Name	Everolimus
Synonyms	42-O-(2-Hydroxyethyl)-rapamycin 42-O-(2-Hydroxy)ethylrapamycin
CAS	159351-69-6
Molecular Formula	C₅₃H₈₃NO₁₄
Molecular Weight	958.232
Density	1.18
Boiling Point	998.7°C at 760 mmHg
Flash Point	557.8 °C
Storage	−20°C
Refractive Index	1.548
Appearance	White powder
Solubility	Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.

Description:

Everolimus is a derivative of Rapamycin(sirolimus), and works similarly to Rapamycin as an mTOR(mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors, Everolimus takes effect solely on the mTORC1 protein and not on the mTORC2 protein. In transplantation medicine, it is marketed under the trade names Zortress(USA) and Certican(Europe). It has been also used for the treatment of tumors, being marketed as Afinitor(general tumours) and Votubia(tumours as a result of TSC) in oncology.

Function:

Everolimus is indicated for the treatment of the following patients:
1. Adult patients with advanced renal cell carcinoma who have failed to receive either sunitinib or sorafenib.
2. Unresectable, locally advanced or metastatic, well-differentiated (moderately differentiated or highly differentiated) advanced pancreatic neuroendocrine tumors in adult patients.
3. Adult and pediatric patients with subsegmental giant cell astrocytoma (SEGA) associated with tuberous sclerosis (TSC) requiring therapeutic intervention but not suitable for surgical resection. The effectiveness of this product is primarily demonstrated by sustainable objective relief (ie, the reduction in SEGA tumor volume). Patients with subsegmental giant cell astrocytoma associated with tuberous sclerosis have not been shown to have improved disease-related symptoms and prolonged overall survival.

FAQ

Q1. Are you a manufacturer

Answer: Yes, we have our own factory and lab.

Q2. Do you have GMP or DMF

Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.

Q3. What information should I let you know if I want to get a quotation

Answer: -Quality you require, eg. Assay, Purity, or single impurity

-Quantity you need

-Standard you want, such as USP, EP, JP etc.

Q4. How to make the payment

Answer: Escrow and T/T in advance are highly recommended. We can accept , Money Gram and Paypal as well.

Q5. When will you deliver the goods

Answer: For sample, in about 2 working days after payment; for larger orders (more than 1kg), in about 5 working days after payment.

Q6. How will you deliver the goods

Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping.

You also can choose your own shipping forwarder.

Q7. When will we receive the goods

Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.

Q8. What if we find your products unsatisfied

Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.