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Capecitabine Capecitabine 99% 154361-50-9
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Product Name |
Capecitabine |
CAS |
154361-50-9 |
Molecular Formula |
C15H22FN3O6 |
Molecular Weight |
359.35 |
Density |
1.49g/cm3 |
Melting Point |
110-121°C |
Boiling Point |
437.874°C at 760 mmHg |
Flash Point |
218.619°C |
Refractive Index |
1.7 |
Vapour Pressure |
0mmHg at 25°C |
Storage |
-20°C Freezer |
Solubility |
H2O: soluble10mg/mL, clear (warmed) |
Appearance |
White powder |
Capecitabine is mainly used for advanced breast cancer and colorectal cancer, and can be used as the rescue treatment for breast cancer after the failure of anthracycline and yew treatment
Quickly via the intestinal mucosa absorption after oral Capecitabine, and then by carboxylic ester in liver enzyme into inactive intermediate 5 '- DNA - 5' fluorine cytidine, by the liver and tumor tissues after cytidine deaminase into the action of 5 '- DNA - 5' floxuridine, finally in tumor tissue Canon thymidine phosphorylase catalysis of fluorouracil (5 - FU).
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