CasNo.98-96-4,CAS 98-96-4 Pyrazinecarboxamide / Pyrazinamide,Pyrazinamide(98-96-4) Suppliers

0	Negotiable

Min.Order :0
Purity: 99%

Keywords

Pyrazinamide Pyrazinecarboxamide 98-96-4

Quick Details

Appearance:White to off-white crystal powder
Application:Mainly use in pharmaceutical intermediates/medical intermediate/ research purpose
PackAge:Aluminum foil bag,fluorinated bottles,carboard drums or as your special request.
ProductionCapacity:
Storage:Store in cool & dry place. Keep away from strong light Shelf Life2 years when properly stored.
Transportation:1) Door to Door Service by DHL/FEDEX/EMS/TNT for package under 45kgs, about 3~7 days delivery. 2) Port to Port Service by Air for package more than 45kgs, about 3~7 days delivery. 3) Port to Port...

Superiority:

1) Provide costomers with "one-stop"packaging service,from research,development,production,export and so on.
2) We have our own R&D and production base,equipped with advanced production equipment and precision testing the Unitef States Pharmacopoeia(USP),the Britis Pharmacopoeia(EP) and other international advanced standards.All products are through the KOSGER,HALAL certification,the ISO quality management system certification and the HACCP certification.
3) More than 12 years of export experience.
4)Competitive price in China market.

Details:

It is a white or off-white crystalline powder; it is odorless or almost odorless and has a slightly bitter taste. Slightly soluble in water, very slightly soluble in ethanol. The melting point is 188~192 °C, which has a good antibacterial effect on human tuberculosis bacillus. At pH 5~5.5, the bactericidal effect is the strongest. The antibacterial concentration in the human body is 12.5 μg/ml, and 50 μg/ml can kill Mycobacterium tuberculosis. The mechanism of action may be related to pyrazinic acid. Pyrazinamide penetrates into phagocytic cells and enters the Mycobacterium tuberculosis. The amidase in the bacteria removes the amide group and converts it into pyrazine acid to exert an antibacterial effect. In addition, pyrazinamide is similar in chemical structure to nicotinamide, and interferes with dehydrogenase by substituting nicotinamide to prevent dehydrogenation, hindering the utilization of oxygen by tubercle bacilli, and affecting the normal metabolism of bacteria and causing death.