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Ascomycin fk520 fk 520
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Factory supply 99% Ascomycin/FK-520 Cas: 11011-38-4
Ascomycin | |
CAS No.: | 11011-38-4 |
Synonyms: | IMMUNOMYCIN; |
FK-520; | |
ASCOMYCIN /IMMUNOMYCIN/FR-900520/FK-520; | |
AAG; | |
ASCOMYCIN,STREPTOMYCES HYGROSCOPICUS; | |
Formula: | C43H69NO12 |
Exact Mass: | 791.48200 |
Molecular Weight: | 792.00700 |
Appearance & Physical State: | White Powder |
Melting Point: | 156 -161ºC |
Ascomycin (also known as Immunomycin) is an analog of tacrolimus with immunosuppressive, neurotrophic and antifungal activities. Ascomycin can be used to prevent rejection after an organ transplant, and to treat autoimmune diseases and skin diseases. Ascomycin inhibits the production of T helper type 1 and cytokines in target cells.
Specification:
TEST | SPECIFICATION | RESULT |
Appearance | White to off-white crystals | White crystals |
Identification | 1-HNMR: Consistent with the standard | Conforms |
IR: The IR absorption spectrum of the sample must be concordant with test Standard. | Conforms | |
HPLC: The HPLC spectrum of the sample must be concordant with the standard substance. | Conforms | |
Residue on ignition | NMT 0.2% | 0.02% |
Water | NMT 2.0% | 0.06% |
Heavy Metals | NMT 20ppm | 5ppm |
Related Substance | Impurity A: NMT 0.2% | 0.07% |
Impurity B: NMT 0.15% | 0.03% | |
Impurity C: NMT 0.15% | 0.07% | |
Any other impurity: NMT 0.10% | N.D. | |
Total impurities: NMT 1.0% | 0.17% | |
Residual Solvents | Methanol: NMT 0.3% | N.D. |
Ethanol: NMT 0.5% | N.D. | |
Ethyl acetate: NMT 0.5% | N.D. | |
Assay(By HPLC) | 98.0%~102% | 99.84% |
Storage | Store in a tightly closed container in a cool and dry place, below | |
Conclusion | Confirm to enterprise standard |
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