2-Methoxyethoxymeth...

2-Methoxyethoxymethyl chloride
2-Methoxyethoxymethyl chloride
2-Methoxyethoxymethyl chloride

2-Methoxyethoxymethyl chloride

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1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

API Pharmaceutical Intermediate Roxithromycin

Quick Details

  • Appearance:Clear colorless to yellow liquid
  • Application:API
  • PackAge:As required
  • ProductionCapacity:5|Metric Ton|Month
  • Storage:Store in dry, dark and ventilated place
  • Transportation:by sea or by air

Superiority:

Changzhou Xuanming Chemical Co., Ltd. is dedicated to the technology development, manufacturing, import and export chemicals, which are specialized in pharmaceutical intermediates, pesticide intermediate, industry of fine chemicals and custom synthesis. Now, we enjoy good reputation among customers and take favorable market share in domestic and at abroad.

Changzhou Xuanming Chemical CO., LTD is located in Northern Jiangshu Industry Park, we have modern manufacture bases and some laboratories, which can supply the key intermediate for your projects, and short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard. We have been abided by “treat technology as first, quality as basis, customers as God, and be honest and sincere”. It is our final aim to provide environmental and high technological products and meet customers’ requirements according to keep effors on developing new chemical fields.

Changzhou Xuanming Chemical CO., LTD promises to help you with heart and soul.

Details:

2-Methoxyethoxymethyl chloride Basic information
Product Name: 2-Methoxyethoxymethyl chloride
Synonyms: 1-Chloromethoxy-2-methoxyethane Ethylene Glycol Chloromethyl Methyl Ether MEM-Chloride;2,5-Dioxahexyl chloride, tech;MEM chloride, 1-(Chloromethoxy)-2-methoxyethane, 2-Methoxyethoxymethyl chloride;MethoxyethoxyMethylchlorid;1-(chloromethoxy)-2-methoxy-ethan;1-Chloro-2,5-dioxahexane;BETA-METHOXYETHOXYMETHYL CHLORIDE;ETHYLENE GLYCOL CHLOROMETHYL METHYL ETHER
CAS: 3970-21-6
MF: C4H9ClO2
MW: 124.57
EINECS: 223-589-8
Product Categories: -;Protection & Derivatization Reagents (for Synthesis);Synthetic Organic Chemistry
Mol File: 3970-21-6.mol
2-Methoxyethoxymethyl chloride Structure
 
2-Methoxyethoxymethyl chloride Chemical Properties
Melting point  200-202 °C
Boiling point  50-52 °C13 mm Hg(lit.)
density  1.091 g/mL at 25 °C(lit.)
refractive index  n20/D 1.427(lit.)
Fp  >230 °F
storage temp.  −20°C
form  Liquid
Specific Gravity 1.091
color  Clear colorless to yellow
Water Solubility  It hydrolyzes with water.
Sensitive  Moisture Sensitive
BRN  1900576
InChIKey BIAAQBNMRITRDV-UHFFFAOYSA-N
CAS DataBase Reference 3970-21-6(CAS DataBase Reference)
NIST Chemistry Reference «BETA»-methoxyethoxymethyl chloride(3970-21-6)
EPA Substance Registry System Ethane, 1-(chloromethoxy)-2-methoxy- (3970-21-6)
 
Safety Information
Hazard Codes  T
Risk Statements  45-10-36/37/38-20/21/22-46-40-23/24/25-20/22
Safety Statements  53-26-36/37/39-45-16-23
RIDADR  UN 2810 6.1/PG 2
WGK Germany  3
F  10-21
Hazard Note  Toxic
TSCA  Yes
HazardClass  3
PackingGroup  III
HS Code  29091990
 
2-Methoxyethoxymethyl chloride Usage And Synthesis
Chemical Properties CLEAR COLOURLESS LIQUID
Uses 2-Methoxyethoxymethyl Chloride is an OH-protecting reagent. 2-Methoxyethoxymethyl Chloride is used in the modification of antibiotics.
Purification Methods Possible impurities are methoxyethanol (b 124o/atm), HCHO and HCl which can be removed below the boiling point of MEMCl. Purify MEMCl by fractional distillation in a vacuum. If too impure, prepare it from methoxyethanol (152g) and s-trioxane (66g) by bubbling a stream of dry HCl (with stirring) until a clear mixture is obtained. Dilute with pentane (900mL), dry (3hours over 100g MgSO4, at 5o), evaporate and the residue is distilled in a vacuum. It is MOISTURE SENSITIVE and TOXIC. The MEM.NEt3+Cl-salt, prepared by reaction with 1.3 equivalents of Et3N (16hours/25o) and dried in a vacuum, has m 58-61o, and is moisture sensitive. [Corey et al. Tetrahedron Lett 809 1976, Yoshimatsu et al. J Org Chem 59 1011 1994, Greene & Wuts Protective Groups in Organic Synthesis edn, J Wiley & Sons NY 1991.] Carcinogen.
 

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