tributyl O-acetylci...

tributyl O-acetylcitrateCAS NO.: 77-90-7

tributyl O-acetylcitrateCAS NO.: 77-90-7

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1 Kilogram

FOB Price:USD 3.0000 -6.0000

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram,Other

Keywords

Acetyl tributyl citrate high purity Acetyl tributyl citrate 99.5% Acetyl tributyl citrate

Quick Details

  • Appearance:colourless liquid
  • Application:Catalyst and Auxiliary
  • PackAge:Aluminium Foil Bag and Paper Drum
  • ProductionCapacity:10000|Gram|Day
  • Storage:Room temperature
  • Transportation:By sea or by air

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Details:

Chemical Properties clear colorless liquid
Chemical Properties Acetyltributyl citrate is a clear, odorless, practically colorless, oily liquid.
Chemical Properties Tributyl acetylcitrate has a very faint, sweet, herbaceous odor. At high levels (e.g., 1000 ppm emulsion in water), it has a mild, fruity, nondescript flavor.
Chemical Properties Acetyl tributyl citrate (ATBC) is a colorless, odorless liquid. Its water solubility is less than 0.002 g/100 mL, but it is soluble in organic solvents.
Uses Labelled Tributyl O-Acetylcitrate (T772950). Topical pharmaceutical formulation anesthetic surfactant ester.
Uses plasticizer flavoring agent
Definition Aqueous-based pharmaceutical coat- ings.
Preparation From citric acid via the tributyl ester followed by acetylation.
Production Methods Acetyltributyl citrate is prepared by the esterification of citric acid with butanol followed by acylation with acetic anhydride.
Pharmaceutical Applications Acetyltributyl citrate is used to plasticize polymers in formulated pharmaceutical coatings, including capsules, tablets, beads, and granules for taste masking, immediate release, sustained-release and enteric formulations.
Safety Profile When heated to decomposition it emits acrid smoke and irritating fumes. ADD750
Safety and films intended for direct food contact. It is also used in selfadhesive thin films used for topical delivery systems. It is generally regarded as a relatively nontoxic and nonirritating material. However, ingestion of large quantities may be harmful.
LD50 (cat, oral): >50 mL/kg
LD50 (mouse, IP): >4 g/kg
LD50 (rat, oral): >31.5 g/kg
Carcinogenicity The chronic toxicity of ATBC was evaluated in rats fed diets containing 200, 2000, or 20,000 ppm of ATBC for 2 years. There were no treatment- related lesions in any organs examined.
storage Acetyltributyl citrate should be stored in a well-closed container in a cool, dry location at temperatures not exceeding 38℃. When stored in accordance with these conditions, acetyltributyl citrate is a stable product.
Incompatibilities Acetyltributyl citrate is incompatible with strong alkalis and oxidizing materials.
Regulatory Status Included in FDA Inactive Ingredients Database (oral capsules and tablets). Included in nonparenteral medicines licensed in the UK. Approved in the USA for direct food contact in food films.

 

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