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Miconazole nitrate 1-(2,4-dichloro-beta-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole nitrate 22832-87-7
Product Name: Miconazole Nitrate
Purity: 98%min by HPLC
CAS No.: 22832-87-7
Appearance: White powder
M.W.: 479.14
M.F.: C18H15CI4N3O4
Miconazole nitrate is an antifungal synthetic derivative of imidazole and used in the treatment of candidal skin infections, Miconazole selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalian cells membranes.
Specification |
Standard |
|
Appearance |
White or almost white crystal powder |
|
Identification |
Ir |
Similar to standard |
Appearance of solution |
The solution is clear and not more intensely cloured than reference solutions Y7 |
|
Solubility |
Very slightly soluble in water; soluble in methanol; slightly soluble in alcohol |
|
Angle of optical rotation |
-0.10 ----+0.10 |
|
Related substances |
Each impurity |
≤0.25% |
Total imurity |
≤0.5% |
|
Melting point |
178-182°C |
|
Loss on drying |
≤0.5% |
|
Residue on ignition |
≤0.1% |
|
Assay ( on dry basis) |
99.5-101% |
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