Tyrphostin AG 490 Tyrphostin B42 stem cell
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AG-490 is an inhibitor of tyrosine kinases including EGFR, HER2, JAK2, JAK3, and STAT5a/b with IC50 values of 0.1, 13.5, 11 and 12 μM, respectively. It was shown to induce apoptosis in myeloma cells.
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