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Keywords
WHI-P 154 JAK3 inhibitor II stem cell
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BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
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WHI-P154 is a JAK3 inhibitor with IC50 value of 1.8 μM. It also inhibits other kinases including EGFR (IC50 = 4 nM), Src, Abl, VEGFR, MAPK and PI 3-K and induces apoptosis in human glioblastoma cell lines. It enhances differentiation of neural progenitor cells.
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